Antral (antral) coated tablets 0.2 g. №30

Antral (antral) coated tablets 0.2 g. №30

$24.00

Manufacturer: Ukraine

Antral is indicated for adults and children for the treatment of:

  • acute and chronic hepatitis of various origins (viral, alcoholic, drug, toxic);
  • fatty degeneration and cirrhosis of the liver;
  • inflammatory diseases of the gallbladder, spleen, pancreas;
  • postcholecystectomy syndrome (after removal of the gallbladder).

And also for the prevention of liver diseases due to the negative effects of toxins of various etiologies: alimentary toxins, drugs, chemotherapy, radiation therapy.

Category:

Description

Ingredients

active ingredient : 1 tablet contains antral in terms of dry matter 100 mg (0.1 g) or 200 mg (0.2 g);

excipients : heavy magnesium carbonate, potato starch, crospovidone, microcrystalline cellulose, povidone, polysorbate, anhydrous colloidal silicon dioxide, calcium stearate, Opadry II 85 G18490 white, Opadry II 85 G25557 red.

Dosage form

Coated tablets.

Basic physical and chemical properties:  round-shaped tablets with a biconvex surface, film-coated dark red.

Pharmacotherapeutic group

Hepatoprotective drugs. ATX code A05V A.

Pharmacodynamics

Antral belongs to the group of hepatoprotective drugs. It is effective in the treatment of acute and chronic hepatitis of various origins, cirrhosis of the liver, helps to reduce asthenovegetative disorders, improves appetite, sleep, and reduces dyspepsia. With a course application, the drug normalizes the content of bilirubin, γ-globulins, cholesterol in the blood, prothrombin index, activity of transaminases (AlAT and AsAT) and alkaline phosphatase.

Antral has prolonged anti-inflammatory, analgesic effects. According to the results of preclinical studies, it was found that Antral in conditions of acute, subacute and chronic liver damage by various xenobiotics and their combinations helps to reduce the effects of hepatotoxins, activate reparative processes in hepatocytes and practically normalize the indicators of the structural and functional state of the liver.

The drug inhibits the processes of lipid peroxidation in the blood and tissues, maintains the activity of the body’s antioxidant systems, and stabilizes the structure of the liver and hepatocyte membranes. Being a relatively harmless pharmacological agent, Antral does not disrupt the functions of organs and systems of the body, it does not have cumulative properties, immunotoxic, locally irritating, allergenic, ulcerogenic, embryotoxic, teratogenic effects.

Indications

Antral coated tablets are indicated for adults and children for the treatment of:

  • acute and chronic hepatitis of various origins (viral, alcoholic, drug, toxic);
  • fatty degeneration and cirrhosis of the liver;
  • inflammatory diseases of the gallbladder, spleen, pancreas;
  • postcholecystectomy syndrome (after removal of the gallbladder).

And also for the prevention of liver diseases due to the negative effects of toxins of various etiologies: alimentary toxins, drugs, chemotherapy, radiation therapy.

Contraindications

  • Individual hypersensitivity to the components of the drug.
  • Violation of the excretory function of the kidneys.

Dosage and administration

Antral coated tablets are administered orally after meals 3 times a day:

  • adults and children from 10 years old – 200 mg per dose; with cirrhosis of the liver: in the first week of treatment – 400 mg per dose, then within 2-3 weeks – 200 mg per dose;
  • children 4-10 years old (including those with cirrhosis of the liver) – 100 mg per dose.

The duration of treatment depends on the nature and severity of the disease. The average course of treatment is 3-4 weeks. The course of treatment should be repeated after 3-4 weeks.

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