Description
Arduan (Pіpekuronіy Bromid) Lyophilisate for Solution for Injections 4 mg Vial №25
Composition
Arduan contains pіpekuronіy bromid as the active ingredient.
Mechanism of Action
Pharmacologically, pіpekuronіy bromid acts by competitively blocking the action of acetylcholine at the neuromuscular junction, leading to muscle paralysis. This effect is reversible with the administration of acetylcholinesterase inhibitors postoperatively.
Indications for Use
Arduan is indicated for use as a neuromuscular blocking agent to facilitate endotracheal intubation and provide skeletal muscle relaxation during surgery or mechanical ventilation.
Contraindications
Arduan is contraindicated in patients with a known hypersensitivity to pіpekuronіy bromid or any of the other ingredients in the formulation.
Side Effects
Common side effects of Arduan may include respiratory depression, hypotension, and hypersensitivity reactions. It is important to monitor patients closely for any adverse reactions.
Usage Instructions
Arduan should only be administered by healthcare professionals trained in the use of neuromuscular blocking agents. The injection should be given intravenously and the patient should be monitored closely during and after administration.
Benefits Compared to Analogues
Clinical trials have shown that Arduan has a rapid onset of action and a relatively short duration, making it a valuable option for procedures requiring muscle relaxation. Compared to other neuromuscular blocking agents, Arduan offers a favorable profile of efficacy and safety.
Suitable Patient Groups
Arduan is suitable for adult patients requiring muscle relaxation during surgical procedures. It should be used with caution in patients with conditions that may be exacerbated by muscle relaxation, such as myasthenia gravis or neuromuscular disorders.
Storage and Shelf Life
Store Arduan according to the manufacturer’s instructions. Check the expiration date on the packaging and do not use the product beyond this date.
Packaging Description
Arduan is available in vials containing 4 mg of pіpekuronіy bromid for injection. Each package contains 25 vials.
Clinical Evidence and Proven Effectiveness
Studies have shown that pіpekuronіy bromid, the active ingredient in Arduan, is effective in providing rapid and reliable muscle relaxation for intubation and surgical procedures. Research published in the Journal of Anesthesia and Analgesia demonstrated the efficacy of pіpekuronіy bromid in achieving optimal conditions for tracheal intubation.
