Description

Arifon Retard (indapamide) tablets coated 1.5 mg. №30

Ingredients

Each tablet contains 1.5 mg of indapamide as the active ingredient.

Dosage

The usual dose is one tablet daily, preferably taken in the morning with or without food.

Indications

Arifon Retard is indicated for the treatment of hypertension. It helps lower blood pressure by promoting the excretion of sodium and water.

Contraindications

Do not use Arifon Retard if you are allergic to indapamide or if you have severe kidney disease. It is also contraindicated in patients with a history of gout.

Directions

Swallow the tablet whole with a glass of water. Do not crush or chew the tablet. Follow the instructions of your healthcare provider for the best results.

Scientific Evidence

Studies have shown that indapamide, the active ingredient in Arifon Retard, is effective in lowering blood pressure and reducing the risk of cardiovascular events. A meta-analysis published in the Journal of Hypertension concluded that indapamide-based therapies significantly reduce the incidence of stroke and overall mortality in hypertensive patients.

Additional Information

Arifon Retard is a sustained-release formulation, providing long-lasting blood pressure control with once-daily dosing. It is well-tolerated with a low incidence of side effects, making it a preferred choice for many patients with hypertension.

Indapamide works by inhibiting sodium reabsorption in the distal convoluted tubules of the kidneys, leading to diuresis and vasodilation. This dual action helps to reduce blood pressure without significant electrolyte disturbances.