Description
Arifon Retard (Indapamide) Tablets Coated 1.5 mg. №30
Composition
Each tablet contains 1.5 mg of indapamide as the active ingredient.
Mechanism of Action
Indapamide acts by inhibiting sodium reabsorption in the distal convoluted tubules of the kidneys, resulting in diuresis and vasodilation. This dual mechanism helps to reduce blood pressure without causing significant electrolyte imbalances.
Pharmacological Properties
Arifon Retard contains indapamide, a thiazide-like diuretic that exerts antihypertensive effects by enhancing the excretion of sodium and water, thereby reducing blood volume and lowering blood pressure.
Indications for Use
Arifon Retard is indicated for the treatment of hypertension. It aids in lowering blood pressure by facilitating the elimination of sodium and water from the body.
Contraindications
Avoid using Arifon Retard if you are allergic to indapamide or if you suffer from severe kidney disease. Additionally, individuals with a history of gout should not take this medication.
Side Effects
Common side effects of Arifon Retard may include dizziness, headache, electrolyte disturbances, and gastrointestinal upset. Contact your healthcare provider if you experience any severe or persistent side effects.
Usage Instructions
Take one tablet of Arifon Retard daily, preferably in the morning, with or without food. Swallow the tablet whole with a glass of water; do not crush or chew it. Adhere to your healthcare provider’s instructions for optimal results.
Benefits Compared to Analogues
Arifon Retard offers sustained-release formulation for long-lasting blood pressure control with once-daily dosing. Its favorable tolerability profile and minimal side effects make it a preferred choice among patients with hypertension compared to other antihypertensive medications.
Suitable Patient Groups
Arifon Retard is suitable for adult patients with hypertension. It should be used with caution in elderly individuals and avoided in pediatric populations due to limited safety and efficacy data in these groups.
Storage and Shelf Life
Store Arifon Retard in a cool, dry place away from direct sunlight. Keep the medication in its original packaging to protect it from moisture. Check the expiration date on the packaging and do not use the product beyond the stated shelf life.
Packaging Description
Arifon Retard is available in blister packs containing 30 tablets. Each tablet is coated for ease of swallowing and protection of the active ingredient.
Clinical Evidence and Proven Effectiveness
Studies have demonstrated the efficacy of indapamide in reducing blood pressure and lowering the risk of cardiovascular events. A meta-analysis published in the Journal of Hypertension showed that therapies containing indapamide significantly decrease the incidence of stroke and overall mortality in hypertensive patients.
