Description

Ariprazol (aripiprazole) Tablets 15 mg. №30

Ingredients:

Ariprazol tablets 15 mg contain aripiprazole as the active ingredient.

Mechanism of Action:

Aripiprazole exerts its therapeutic effect through a combination of partial agonist activity at dopamine D2 and serotonin 5-HT1A receptors, and antagonist activity at serotonin 5-HT2A receptors.

Pharmacological Properties:

Ariprazol demonstrates high affinity for dopamine D2 and D3, serotonin 5-HT1A and 5-HT2A, and adrenergic α1 receptors. It also exhibits moderate affinity for histamine H1 receptors.

Indications for Use:

Ariprazol tablets are indicated for the treatment of schizophrenia and bipolar disorder in adults.

Contraindications:

Ariprazol tablets should not be used in individuals with a known hypersensitivity to aripiprazole or any other components of the product. Caution is advised in patients with a history of neuroleptic malignant syndrome.

Side Effects:

Common side effects of aripiprazole may include nausea, constipation, headache, dizziness, and somnolence. Serious side effects such as tardive dyskinesia and metabolic changes may also occur.

Usage Instructions:

The recommended dosage of Ariprazol tablets is 15 mg once daily, with or without food. Dosage adjustments may be necessary based on individual response and tolerability.

Benefits Compared to Analogues:

Ariprazol offers the advantage of a unique pharmacological profile with partial agonist activity, potentially reducing the risk of certain side effects associated with traditional antipsychotics.

Suitable Patient Groups:

Ariprazol is suitable for use in adult patients with schizophrenia and bipolar disorder. Dosing adjustments may be required in elderly patients or those with hepatic impairment.

Storage and Shelf Life:

Store Ariprazol tablets at controlled room temperature between 20-25°C (68-77°F). Protect from light and moisture. The shelf life of the product is as indicated on the packaging.

Packaging Description:

Ariprazol tablets are typically packaged in blister packs of 30 tablets each, clearly labeled with product information and expiry date.

Scientific Evidence:

Ariprazol has been extensively studied in clinical trials for its efficacy in schizophrenia and bipolar disorder. Clinical studies have shown that aripiprazole effectively reduces symptoms of psychosis and mania, with a favorable side effect profile compared to other antipsychotic agents.

Additional Information:

Regular monitoring by healthcare providers is crucial during aripiprazole treatment to ensure optimal therapeutic outcomes. Patients should report any adverse effects or concerns to their healthcare provider promptly.