Description

Aris (Meropenem) Powder for Infusions 1g – Vial №1

Composition:

Each vial contains 1g of meropenem.

Mechanism of Action:

Meropenem, a broad-spectrum carbapenem antibiotic, exerts its bactericidal effects by inhibiting the synthesis of bacterial cell walls, leading to cell death.

Pharmacological Properties:

Meropenem exhibits potent activity against a wide range of Gram-positive and Gram-negative bacteria, including strains resistant to other antibiotics. It penetrates well into various tissues and body fluids, ensuring effective treatment of infections.

Indications for Use:

Aris (Meropenem) is indicated for the treatment of severe bacterial infections, such as intra-abdominal infections, skin and soft tissue infections, pneumonia, and meningitis caused by susceptible pathogens.

Contraindications:

Do not administer Aris (Meropenem) if the patient has a known hypersensitivity to meropenem, other beta-lactam antibiotics, or any component of the formulation. Caution is advised in patients with a history of allergic reactions to beta-lactams.

Side Effects:

Common side effects of Aris (Meropenem) may include diarrhea, nausea, vomiting, headache, rash, and injection site reactions. Serious but rare adverse effects may include severe allergic reactions, seizures, and Clostridium difficile-associated diarrhea.

Usage Instructions:

The recommended dosage of Aris (Meropenem) should be individualized based on the severity of the infection, patient’s renal function, and susceptibility of the causative pathogens. It is typically administered intravenously over a specific duration, often every 8 hours. Healthcare professionals should follow aseptic techniques during preparation and administration.

Benefits Compared to Analogues:

Meropenem has a broader spectrum of activity compared to other antibiotics, making it effective against a wide array of pathogens, including multidrug-resistant bacteria. Its stability against many beta-lactamases enhances its efficacy in challenging infections.

Suitable Patient Groups:

Aris (Meropenem) can be used in pediatric and adult populations, including elderly patients and those with compromised renal function. Dosing adjustments may be necessary in patients with renal impairment to prevent drug accumulation and toxicity.

Storage and Shelf Life:

Aris (Meropenem) should be stored at controlled room temperature away from light and moisture. The shelf life of the product is typically mentioned on the packaging and should be strictly adhered to for optimal efficacy.

Packaging Description:

The product is supplied in vials containing 1g of Meropenem powder for reconstitution. Each vial is labeled with essential information, including dosage instructions, batch number, and expiration date.

Clinical Evidence and Proven Effectiveness:

Meropenem has been extensively studied in clinical trials, demonstrating high efficacy rates and favorable outcomes in the treatment of various severe bacterial infections. Its ability to penetrate tissues and combat resistant strains makes it a valuable therapeutic option.