Artiflex (chondroitin sulfate) Chondro solution for injections 100 mg/ml. 2 ml. №10

active ingredient: chondroitin sulfate;

1 ml chondroitin sulfate sodium 100 mg;

excipients: benzyl alcohol, water for injection.

Injection.

Basic physical and chemical properties: transparent colorless or slightly yellowish liquid with the smell of benzyl alcohol.

Drugs that affect the musculoskeletal system. Chondroitin sulfate. ATX code M01A X25.

The main active ingredients of Artiflex Khondro (chondroitin sulfate) are sodium salts of chondroitin sulfate A and C (average molecular weight 11,000 daltons). Chondroitin sulfate is a high molecular weight mucopolysaccharide. It is the main component of proteoglycans, which together with collagen fibers form the cartilage matrix.

The drug inhibits the process of degeneration and stimulates the regeneration of cartilaginous tissue, has a chondroprotective, anti-inflammatory, analgesic effect. Replaces chondroitin sulfate of articular cartilage, catabolization by a pathological process. Suppresses the activity of enzymes that cause degradation of articular cartilage; inhibits metalloproteinases, namely leukocyte elastase. Reduces the activity of hyaluronidase. Partially blocks the release of free oxygen radicals, helps to block chemotaxis, antigenic determinants. Stimulates the production of proteoglycans by chondrocytes. Affects phosphorus-calcium metabolism in cartilaginous tissue. Allows you to restore the mechanical and elastic integrity of the cartilage matrix.

The use of the drug helps to restore the joint capsule and cartilaginous surfaces of the joints, prevents compression of the connective tissue, acts as a lubricant for the articular surfaces, normalizes the production of joint fluid, improves joint mobility, helps reduce pain intensity, and improves quality of life.

Artiflex Khondro (chondroitin sulfate) slows down the resorption of bone tissue and reduces the loss of calcium, accelerates the process of restoration of bone tissue.

After the introduction of chondroitin sulfate penetrates into the synovial fluid. Cmax in the synovial fluid is reached 4-5 hours after injection. It is excreted from the body within 24 hours. It is excreted mainly by the kidneys.

Degenerative-dystrophic diseases of the joints and spine (primary arthrosis, intervertebral osteochondrosis, osteoarthritis), osteoporosis, periodontal disease, fractures (to accelerate the formation of callus), as well as to treat the consequences of operations on the joints.

Hypersensitivity to the components of Artiflex Khondro (chondroitin sulfate), a tendency to bleeding, thrombophlebitis, renal failure, liver failure in the stage of decompensation, pregnancy, lactation, childhood.

Use with caution: in case of blood clotting disorders, diabetes mellitus, persons with increased body weight, in violation of kidney function, women planning pregnancy.