$5.00
Manufacturer: Ukraine
Ascorbic acid is used for hypovitaminosis C; scurvy, bleeding (uterine, pulmonary, nasal, hepatic), hemorrhagic diathesis, bleeding like radiation sickness syndrome, various intoxications and infectious diseases, Addison’s crisis, overdose of anticoagulants, bone fractures and flaccid wounds, various dystrophies, increased brain stress and heavy physical labor.
Description
Ingredients
active ingredient: ascorbic acid (vit C);
1 ml of solution contains ascorbic acid 50 mg;
excipients: sodium bicarbonate, anhydrous sodium sulfite (E 221), water for injection.
Dosage form
Injection.
Basic physical and chemical properties: transparent colorless or slightly yellowish liquid.
Pharmacotherapeutic group
Simple preparations of ascorbic acid. Vitamin C. ATX code A11G
Pharmacodynamics
Ascorbic acid (vitamin C) is a water-soluble vitamin that contributes to the optimal course of tissue metabolism. Actively participates in redox reactions, forming a hydrogen proton transfer system with dehydroascorbic acid, exhibits antioxidant properties, due to which it ensures the stability of cell membranes. Participates in the synthesis of the main substance of the connective tissue of the vascular wall, thus preventing the development of hemorrhagic diathesis. It is not synthesized in the human body. With insufficient intake of ascorbic acid with food, bleeding from the gums and mucous membranes develops. Participates in glucose metabolism, cholesterol catabolism, synthesis of steroid hormones. During stress reactions, the content of ascorbic acid in the body and in the tissue of the adrenal glands is significantly reduced, which confirms the participation of ascorbic acid in adaptation reactions. It is able to have an anti-anemic effect due to the effect on iron metabolism. Restores ferric iron to ferrous iron, which is transported in the bloodstream.
Indications
Hypovitaminosis C; scurvy, bleeding (uterine, pulmonary, nasal, hepatic), hemorrhagic diathesis, bleeding like radiation sickness syndrome, various intoxications and infectious diseases, Addison’s crisis, overdose of anticoagulants, bone fractures and flaccid wounds, various dystrophies, increased brain stress and heavy physical labor.
Contraindications
Hypersensitivity to ascorbic acid or to any of the auxiliary components of the drug; diabetes mellitus, increased blood clotting, tendency to thrombosis, thrombophlebitis, urolithiasis (including hyperoxaluria), renal failure, progressive malignant diseases, hemochromatosis, thalassemia, polycythemia, leukemia, sideroblastic anemia, sickle cell anemia, glucose deficiency 6 -phosphate dehydrogenase.
Dosage and administration
Assign intravenously by stream or drip and intramuscularly.
Intravenous bolus injection over 1-3 minutes. For intravenous drip, dissolve a single dose of the drug in 50-100 ml of 0.9% sodium chloride solution and administer by slow infusion at a rate of 30-40 drops per minute.
Intramuscularly injected deep into the muscle.
Doses should be set individually, taking into account the nature and severity of the disease.
Adults and children over 12 years old are usually prescribed 50-150 mg per day. In case of poisoning, increase the daily dose to 500 mg. The maximum single dose is 200 mg, the daily dose is 1 g.
Children under 12 years of age should be prescribed in a daily dose of 5-7 mg / kg of body weight in the form of a 5% solution (0.5-2 ml). Usually for children, daily doses are: age up to 6 months – 30 mg, 6-12 months – 35 mg, 1-3 years – 40 mg, 4-10 years – 45 mg, 11-12 years – 50 mg.
The maximum daily dose is 100 mg.
Special groups of patients. For patients with recurrent kidney stones, the daily dose of ascorbic acid should not exceed 100-200 mg. For patients with severe terminal renal failure (patients on dialysis), the daily dose of ascorbic acid should not exceed 50-100 mg. For patients with deficiency of glucose-6-phosphate dehydrogenase, the daily dose of ascorbic acid should not exceed 100-500 mg.
Recent Reviews