Description

Atorvasterol (atorvastatin) Coated Tablets 40 mg. №30

Ingredients

Each tablet contains 40 mg of atorvastatin.

Dosage

The usual dose is 10-80 mg once daily. Dosage should be individualized according to patient characteristics such as age, gender, and concomitant medications.

Indications

Atorvastatin is indicated for the treatment of hypercholesterolemia and prevention of cardiovascular diseases. It is effective in reducing LDL cholesterol levels and decreasing the risk of heart attacks and strokes.

Contraindications

Do not use in patients with active liver disease or unexplained persistent elevations of serum transaminases. It is also contraindicated in pregnant and breastfeeding women.

Directions

Take one tablet orally with or without food, as directed by your healthcare provider. It is important to follow a healthy diet and exercise regimen while taking atorvastatin.

Scientific Evidence

Atorvastatin, the active ingredient in Atorvasterol tablets, has been extensively studied in various clinical trials. Research has shown that atorvastatin effectively lowers LDL cholesterol levels and reduces the incidence of cardiovascular events. A study published in the New England Journal of Medicine demonstrated the significant benefits of atorvastatin in reducing the risk of heart attacks and strokes in high-risk patients.

Additional Information

It is important to regularly monitor liver function tests while taking atorvastatin to detect any potential adverse effects on the liver. Common side effects may include muscle pain and weakness, which should be reported to your healthcare provider. If you experience any signs of allergic reactions such as rash, swelling, or difficulty breathing, seek immediate medical attention.

Pharmacological Effects: Atorvastatin works by inhibiting HMG-CoA reductase, an enzyme involved in cholesterol synthesis. By lowering LDL cholesterol levels, atorvastatin reduces the risk of atherosclerosis and cardiovascular events.

Clinical Trials: Clinical trials have shown that atorvastatin is highly effective in reducing LDL cholesterol and improving cardiovascular outcomes. A meta-analysis published in the Journal of the American College of Cardiology confirmed the significant benefits of atorvastatin in primary and secondary prevention of cardiovascular diseases.