Description
Attento (Olmesartan Medoxomil) Coated Tablets 40 mg/10 mg. №28
Ingredients
Each coated tablet contains 40 mg of olmesartan medoxomil and 10 mg of an additional ingredient.
Mechanism of Action
Olmesartan medoxomil acts as an angiotensin II receptor antagonist, selectively blocking the binding of angiotensin II to its receptor. By inhibiting this interaction, olmesartan medoxomil prevents the vasoconstrictor and aldosterone-secreting effects of angiotensin II, leading to vasodilation and decreased blood pressure.
Pharmacological Properties
Olmesartan medoxomil is a prodrug that is rapidly converted to its active form, olmesartan, in the body. Olmesartan selectively inhibits the angiotensin II type 1 receptor, exerting antihypertensive effects by reducing peripheral resistance and decreasing blood pressure.
Indications for Use
Attento tablets are indicated for the treatment of hypertension to lower blood pressure in adults.
Contraindications
Avoid the use of Attento tablets in patients who are pregnant, have severe renal impairment, or have a known hypersensitivity to olmesartan medoxomil or any component of the formulation.
Side Effects
Common side effects of Attento tablets may include dizziness, headache, fatigue, and gastrointestinal disturbances. Patients should report any persistent or severe side effects to their healthcare provider.
Usage Instructions
The recommended dosage of Attento is one tablet daily, with or without food, or as directed by a healthcare professional. The tablet should be swallowed whole with a full glass of water at the same time each day to maintain consistent drug levels in the body.
Benefits Compared to Analogues
Comparative studies have demonstrated that olmesartan medoxomil is as effective as other angiotensin II receptor blockers in reducing blood pressure with a similar safety profile. However, individual response to treatment may vary, necessitating close monitoring and adjustment of therapy under medical supervision.
Suitable Patient Groups
Attento tablets are suitable for use in adult patients with hypertension. Special caution should be exercised when prescribing Attento to elderly patients or individuals with hepatic impairment, and dosage adjustments may be necessary based on individual patient characteristics.
Storage and Shelf Life
Store Attento tablets in a cool, dry place away from direct sunlight and moisture. Keep the tablets in their original packaging to protect them from environmental factors. Check the expiry date on the packaging and do not use the tablets if expired.
Packaging Description
Attento tablets are available in blister packs containing 28 coated tablets. The packaging is designed to maintain the stability and integrity of the tablets throughout their shelf life.
Clinical Evidence and Proven Effectiveness
Studies have shown that olmesartan medoxomil effectively lowers blood pressure by blocking the action of angiotensin II, resulting in vasodilation and reduced vascular resistance. Clinical trials have demonstrated the efficacy and safety of Attento tablets in the management of hypertension, supporting their use as a valuable therapeutic option.
