Auropodox (cefpodoxime) coated tablets 200 mg. №10

Auropodox (cefpodoxime) coated tablets 200 mg. №10

$40.40

Manufacturer: India

Auropodox (cefpodoxime) is used for the treatment of infections caused by pathogens sensitive to the drug, such as infections of ENT organs.

 

Category:

Description

Ingredients

active ingredient : cefpodoxime;

1 film-coated tablet contains cefpodoxime proxetil, equivalent to cefpodoxime 200 mg;

other components: calcium carmellose, lactose monohydrate, hydroxypropylcellulose, sodium lauryl sulfate, crospovidone (type B), corn starch, magnesium stearate, purified water; film coat: hypromellose, titanium dioxide (E 171), West Yellow FCF (E 110), propylene glycol; FD&C red No. 40 (E 129) (for film-coated tablets, 200 mg each); iron oxide yellow (E 172) (for film-coated tablets, 100 mg each).

Dosage form

Film-coated tablets.

Basic physical and chemical properties :

200 mg film-coated tablets: coral to red film-coated tablets, elliptical in shape, embossed with “C” on one side and “62” on the other.

Pharmacodynamics

Cefpodoxime is a well absorbed 3rd generation ester consisting of a racemic mixture of R(+) and S(-) enantiomers. Betalactam antibacterial drug for oral use, a wide spectrum of action. The bactericidal effect of the drug is due to the suppression of the synthesis of the bacterial wall of microorganisms. The drug is active against many gram-positive, gram-negative, aerobic and anaerobic microorganisms. Not destroyed by most beta-lactamases. The spectrum of action of cefpodoxime covers the following microorganisms:

sensitive (aerobic gram-positive bacteria) – Staphylococcus aureus (including penicillinase-producing, but not methicillin-resistant strains), Staphylococcus saprophyticus, Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus agal. (groups C, F, G), Corynebacterium diphtheriae;

sensitive (aerobic gram-negative bacteria) – Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Proteus mirabilis, Proteus vulgaris, Haemophilus influenzae (including beta-lactamase producing strains), Penicillinase producing Haemella), Neisseria meningitidis, Providencia rettgeri, Citrobacter diversus;

sensitive (anaerobic gram-positive bacteria) – Peptostreptococcus magnus;

resistant (aerobic gram-positive bacteria) – Streptococcus pneumoniae (penicillin-resistant strains); Enterococcus spp.; Listeria monocytogenes;

resistant (aerobic gram-negative bacteria) – Enterobacter spp., Pseudomonas spp., Acinetobacter baumanii Clostridium difficile;

resistant (anaerobic Gram-positive bacteria) Bacteroides spp.

The pharmacological action of the drug is due to the properties of cefpodoxime proxetil. Bioequivalence has been proven for all studied parameters.

Indications

Treatment of infections caused by pathogens sensitive to the drug, such as:

  • infections of ENT organs, including sinusitis, tonsillitis, pharyngitis;
  • lower respiratory tract infections, including acute community-acquired pneumonia;
  • acute uncomplicated gonorrhea;
  • uncomplicated urinary tract infections;
  • skin infections, including infected wounds, ulcers, impetigo, abscesses, cellulitis, cellulitis, pyoderma.

Contraindications

Hypersensitivity to drugs of the cephalosporin group, penicillins. Hereditary galactose intolerance, lactase deficiency or glucose/galactose malabsorption syndrome.

Dosage and administration

Tablets are taken orally with meals to enhance absorption.

The duration of treatment depends on the severity of the disease and is determined individually.

Recommended doses for adults and children over 12 years of age with normal kidney function:

Table 1

infections Total daily dose, mg Dosage regimen
ENT infections:

sinusitis;

other infections (including tonsillitis, pharyngitis)

 400

200

 200 mg twice daily 100 mg twice daily
Respiratory tract infections (including acute bronchitis, relapse or exacerbation of chronic bronchitis, bacterial pneumonia) 200-400 (depending on the sensitivity of the pathogen) 200-400 100-200 mg

2 times a day
Uncomplicated urinary tract infections:

upper (acute pyelonephritis);

lower (cystitis)

 400

200

 200 mg 2 times a day

100 mg 2 times a day
Skin and soft tissue infections (abscess, cellulitis, infected wounds, boils, folliculitis, paronychia, carbuncles and ulcers) 400 200 mg 2 times a day
Uncomplicated gonococcal urethritis 200 Disposable

Elderly patients

There is no need to change doses in elderly patients with normal renal function.

Impaired liver function

There is no need to change doses for patients with hepatic insufficiency.

Impaired kidney function

There is no need to change doses for patients with impaired renal function if creatinine clearance is greater than 40 ml / min.

Table 2

Creatinine clearance, ml/min Recommended dose
39-10 100 mg or 200 mg (depending on the type of infection) every 24 hours
<10 100 mg or 200 mg (depending on the type of infection) every 48 hours
Patients on hemodialysis 100 mg or 200 mg (depending on the type of infection) after each dialysis session

Related products