Description

Aurotaz (piperacillin) powder for solution for injections 4.5 g. №1 vial

Ingredients

Active ingredient: Piperacillin sodium. Inactive ingredients may include sodium carbonate, sodium citrate, and hydrochloric acid.

Dosage

Dosage: The usual adult dosage is 3 to 4.5 grams every 4 to 6 hours by intravenous injection.

Indications

Indications: Aurotaz is indicated for the treatment of moderate to severe infections caused by susceptible bacteria.

Contraindications

Contraindications: Do not use Aurotaz if you are allergic to piperacillin or any other beta-lactam antibiotics.

Directions

Directions: Aurotaz is for intravenous use only. It should be reconstituted with a suitable diluent before administration.

Scientific Evidence

Aurotaz (piperacillin) has been extensively studied for its efficacy in treating various bacterial infections. Research published in the Journal of Antimicrobial Chemotherapy has shown that piperacillin is effective against a wide range of gram-positive and gram-negative bacteria, making it a valuable option in the treatment of severe infections.

Additional Information

It is important to complete the full course of treatment with Aurotaz as prescribed by your healthcare provider, even if you start to feel better before the medication is finished. Failure to complete the full course of antibiotics can lead to the development of antibiotic-resistant bacteria.

Pharmacological Effects

Piperacillin, the active ingredient in Aurotaz, is a broad-spectrum antibiotic that works by inhibiting the synthesis of bacterial cell walls. This action leads to the eventual death of the bacteria, effectively treating the infection. Additionally, piperacillin has shown synergistic effects when combined with beta-lactamase inhibitors, enhancing its antibacterial activity.

Clinical Trials and Comparative Effectiveness

Clinical trials have demonstrated the efficacy of Aurotaz in treating various infections, including respiratory tract infections, skin and soft tissue infections, and intra-abdominal infections. Comparative studies have shown that piperacillin is as effective as other broad-spectrum antibiotics in treating severe bacterial infections, with a favorable safety profile.

Overall, Aurotaz (piperacillin) powder for solution for injections 4.5 g. №1 vial is a potent antibiotic with a well-established efficacy in the treatment of moderate to severe bacterial infections. Its broad spectrum of activity, coupled with proven clinical effectiveness, makes it a valuable option for healthcare providers in managing infectious diseases.