Description
Axastrol (Anastrozole) Coated Tablets 1 mg. №28
Composition
Active ingredient: Anastrozole 1 mg.
Other ingredients: Lactose monohydrate, povidone, sodium starch glycolate, colloidal silicon dioxide, magnesium stearate, hypromellose, macrogol 300.
Mechanism of Action
Anastrozole is a selective aromatase inhibitor that inhibits the enzyme aromatase, responsible for converting androgens to estrogens. By reducing estrogen levels, it hinders the growth of hormone receptor-positive breast cancer cells.
Pharmacological Properties
Anastrozole, the active ingredient in Axastrol tablets, exerts its effects by specifically targeting the aromatase enzyme, thereby decreasing estrogen production in postmenopausal women.
Indications for Use
Axastrol tablets are indicated for the adjuvant treatment of postmenopausal women with hormone receptor-positive early breast cancer.
Contraindications
Axastrol tablets should not be used by individuals allergic to anastrozole or any other component of the product. Patients with liver problems should consult a healthcare provider before use.
Side Effects
Common side effects of Axastrol tablets may include hot flashes, joint pain, weakness, sore throat, headache, and nausea. If any severe side effects occur, seek medical attention promptly.
Usage Instructions
The recommended dosage of Axastrol tablets is 1 tablet daily, as directed by a healthcare professional. Swallow the tablet whole with a glass of water, with or without food.
Benefits Compared to Analogues
Anastrozole has demonstrated comparable or superior efficacy to tamoxifen in treating early breast cancer, with a lower incidence of certain adverse effects such as blood clots and endometrial cancer.
Suitable Patient Groups
Axastrol tablets are suitable for postmenopausal women with hormone receptor-positive early breast cancer. The product should be used with caution in patients with liver impairment.
Storage and Shelf Life
Store Axastrol tablets in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use the product if past the shelf life.
Packaging Description
Axastrol tablets are supplied in a pack containing 28 coated tablets, each tablet containing 1 mg of anastrozole. The packaging should be kept intact and out of reach of children.
Clinical Evidence and Proven Effectiveness
Clinical studies have demonstrated the efficacy of anastrozole in reducing the risk of cancer recurrence and improving survival rates in postmenopausal women with hormone receptor-positive early breast cancer. Long-term studies have shown benefits in preventing cancer recurrence.
