Description
Axetin (Cefuroxime) Powder for Injections 750 mg. №10 Vial
Ingredients
Active Ingredient: Cefuroxime. Inactive ingredients may vary.
Mechanism of Action
Pharmacological Properties: Cefuroxime, a second-generation cephalosporin antibiotic, exerts its bactericidal effect by inhibiting bacterial cell wall synthesis. This interference leads to cell death by disrupting the growth and replication of susceptible pathogens.
Indications for Use
Indications: Axetin is indicated for the treatment of infections caused by susceptible strains of bacteria, including respiratory, skin, urinary tract infections, and other bacterial infections.
Contraindications
Contraindications: Avoid using Axetin if you have a known allergy to cefuroxime, other cephalosporins, or any component of the formulation. Caution is advised in patients with a history of severe allergic reactions to beta-lactam antibiotics.
Side Effects
Cefuroxime may cause side effects such as gastrointestinal disturbances, allergic reactions (including anaphylaxis), skin rashes, and hematological abnormalities. Monitoring for adverse reactions and seeking medical advice in case of any unusual symptoms is recommended.
Usage Instructions
Dosage: The standard adult dosage of Axetin is 750 mg to be administered intramuscularly or intravenously every 8 hours. Dosage adjustments may be necessary in patients with renal impairment. Healthcare providers should provide detailed instructions on reconstitution, administration, and monitoring during treatment.
Benefits Compared to Analogues
Research suggests that cefuroxime offers comparable efficacy to other second-generation cephalosporins with a similar safety profile. Its broad spectrum of activity against various pathogens and relatively low incidence of adverse effects make it a preferred choice for many healthcare professionals.
Suitable Patient Groups
Axetin is suitable for adults and elderly patients; however, caution is advised in pediatric populations due to limited safety data. Dosing adjustments based on renal function and individual patient characteristics may be necessary. Consultation with a healthcare provider is essential for personalized treatment plans.
Storage and Shelf Life
It is essential to store Axetin according to the instructions provided on the packaging to maintain its stability and efficacy. The product should be kept at the recommended temperature and protected from light. Always check the expiration date before use and discard any expired medication appropriately.
Packaging Description
Axetin is supplied in vials containing 750 mg of cefuroxime powder for injections. Each package consists of 10 vials, allowing for multiple doses to be prepared and administered as prescribed.
Clinical Evidence and Proven Effectiveness
Axetin (cefuroxime) has been extensively studied in clinical trials, demonstrating significant efficacy against a wide range of bacterial infections. Clinical data supports its effectiveness in treating respiratory, skin, urinary tract infections, and other common bacterial illnesses. High cure rates and favorable outcomes have been reported in patients receiving Axetin therapy.
Additional Information
Completing the full course of Axetin treatment as directed is crucial to achieve optimal therapeutic outcomes, minimize the risk of recurrence, and prevent the development of antibiotic resistance. Patients should adhere to the prescribed regimen and seek medical advice before making any changes to their antibiotic therapy.