Description
Axsef (Cefuroxime) Coated Tablets 500 mg. №20
Ingredients
Each coated tablet contains 500 mg of cefuroxime (as cefuroxime axetil).
Mechanism of Action
Cefuroxime, a second-generation cephalosporin antibiotic, exerts its bactericidal effect by inhibiting bacterial cell wall synthesis. This interference disrupts the integrity of the bacterial cell wall, ultimately leading to bacterial cell death.
Pharmacological Properties
Cefuroxime demonstrates broad-spectrum activity against both Gram-positive and Gram-negative bacteria. Its mechanism of action and pharmacokinetic profile contribute to its efficacy in treating various bacterial infections.
Indications for Use
Axsef (cefuroxime) Coated Tablets are indicated for the treatment of bacterial infections such as respiratory tract infections (including sinusitis and bronchitis), skin and soft tissue infections, urinary tract infections, and other susceptible bacterial conditions. It is essential to use this medication only for bacterial infections as directed by a healthcare professional.
Contraindications
Axsef (cefuroxime) Coated Tablets should not be used in individuals with a known hypersensitivity to cefuroxime or other cephalosporin antibiotics. Patients with a history of severe allergic reactions to beta-lactam antibiotics should avoid the use of cefuroxime. Prior consultation with a healthcare provider is crucial to identify and discuss any potential contraindications.
Side Effects
Common side effects associated with cefuroxime therapy may include gastrointestinal disturbances (such as nausea, vomiting, diarrhea), allergic reactions (rash, itching), and headache. In rare cases, severe allergic reactions like anaphylaxis or Clostridium difficile-associated diarrhea may occur. Patients should promptly report any adverse effects to their healthcare provider.
Usage Instructions
The recommended dosage of Axsef (cefuroxime) Coated Tablets is one 500 mg tablet taken orally twice daily. The dosage regimen may vary depending on the type and severity of the infection. It is crucial to adhere to the prescribed dosage and duration of treatment as instructed by a healthcare professional.
Benefits Compared to Analogues
Cefuroxime offers advantages over some analogues due to its broad spectrum of activity, efficacy against a variety of pathogens, and established safety profile. The convenience of a twice-daily dosing regimen and the availability of coated tablets enhance patient compliance and treatment outcomes.
Suitable Patient Groups
Axsef (cefuroxime) Coated Tablets are suitable for use in adult patients, including the elderly population, and pediatric patients under the guidance of a healthcare provider. Dosage adjustments may be necessary in patients with renal impairment to ensure appropriate drug levels are maintained.
Storage and Shelf Life
Store Axsef (cefuroxime) Coated Tablets at room temperature away from moisture and heat. Ensure proper sealing of the original packaging to protect the tablets from environmental factors. Check the expiration date on the packaging and do not use the tablets beyond the stated shelf life.
Packaging Description
Axsef (cefuroxime) Coated Tablets are typically packaged in blister packs containing 20 tablets. The packaging is designed to maintain the integrity and stability of the tablets, protecting them from external influences that could compromise their quality.
