Description

Azapin (Clozapine) tablets 0.025 g. №50

Ingredients

Active ingredient: Clozapine 0.025 g per tablet.

Dosage

Dosage: The usual starting dose is 12.5 mg once or twice daily, with gradual titration based on individual response.

Indications

Indications: Azapin tablets are indicated for the treatment of severe schizophrenia in patients who have not responded to other medications.

Contraindications

Contraindications: Do not use Azapin if you have a history of agranulocytosis or severe neutropenia.

Directions

Directions: Take Azapin tablets orally with or without food as directed by your healthcare provider.

Scientific Evidence

Clozapine has been extensively studied for its efficacy in treating treatment-resistant schizophrenia. Research has shown that clozapine is superior to other antipsychotic medications in reducing symptoms and improving quality of life in patients with refractory schizophrenia (Meltzer et al., 2012).

Additional Information

Clozapine, the active ingredient in Azapin tablets, exerts its pharmacological effects by antagonizing dopamine receptors in the brain, leading to improved symptoms of schizophrenia. It also has a unique mechanism of action by affecting serotonin, histamine, and muscarinic receptors.

Clinical trials have demonstrated the effectiveness of clozapine in reducing the risk of suicide in patients with schizophrenia compared to other antipsychotic medications (Tiihonen et al., 2006). This highlights the importance of clozapine in managing severe mental health conditions.