Azapin (Clozapine) tablets 0.025 g. №50

Description

Resistant to schizophrenia therapy
Azapine should be prescribed only to those patients with schizophrenia who are resistant to therapy or tolerant to standard antipsychotics according to the following definitions.
Resistance to standard antipsychotics is a condition when previous treatment with standard antipsychotics with the appropriate dosage and for a sufficient period of time did not lead to adequate clinical improvement.
Intolerance to standard antipsychotics is a condition where severe uncontrolled side effects of a neurological nature (extrapyramidal symptoms or tardive dyskinesia) occur that make effective antipsychotic therapy using standard antipsychotics impossible.
Risk of recurrence of suicide attempts
Azapine is indicated for the long-term reduction of the risk of recurrence of suicidal behavior in patients with schizophrenia or schizoaffective disorder who are assessed for this risk based on their medical history and current clinical presentation.
Psychotic Disorders During Parkinson’s Disease Therapy
Azapine is indicated for the treatment of psychotic disorders developing during Parkinson’s disease, if standard therapy is ineffective.
The ineffectiveness of standard therapy is defined as the lack of control over psychotic symptoms and / or the appearance of a functionally unacceptable increase in the severity of motor symptoms after taking the following measures:
withdrawal of anticholinergic drugs, including tricyclic antidepressants;
an attempt to reduce the dose of dopaminergic antiparkinsonian drugs.