Description

Azapin (Clozapine) tablets 0.1g. №50

Ingredients

Active ingredient: Clozapine 0.1g per tablet.

Dosage

Dosage: The usual starting dose is 12.5 mg once or twice daily, gradually increasing. Maximum dose: 900 mg per day.

Indications

Indications: Azapin tablets are indicated for the treatment of severe schizophrenia in patients who have not responded to standard treatments.

Contraindications

Contraindications: Do not use Azapin if you have bone marrow suppression, uncontrolled epilepsy, or a history of clozapine-induced agranulocytosis.

Directions

Directions: Take Azapin tablets orally with or without food as directed by your doctor. Do not suddenly stop taking this medication without consulting your healthcare provider.

Scientific Evidence

Clozapine’s efficacy: Clozapine has shown superior efficacy in treating refractory schizophrenia compared to other antipsychotic medications. Studies have demonstrated its effectiveness in reducing positive and negative symptoms of schizophrenia.

Clinical trials: Clinical trials have highlighted the unique benefits of clozapine, such as its lower risk of extrapyramidal symptoms and potential to improve cognitive function in patients with schizophrenia.

Additional Information

Monitoring: Regular monitoring of white blood cell counts is essential during clozapine treatment due to the risk of agranulocytosis. Patients should also undergo cardiac monitoring due to potential cardiotoxic effects.

Adverse effects: Common side effects of Azapin tablets include sedation, hypersalivation, and weight gain. It is important to discuss the risks and benefits of this medication with your healthcare provider.