Description
B12 (Cyanocobalamin) B12 Ampoules 0.05% 1ml. №10
Ingredients
Each ampoule contains: Cyanocobalamin 0.05% in a 1ml solution.
Mechanism of Action
Cyanocobalamin functions as an essential coenzyme in the conversion of homocysteine to methionine, facilitating DNA synthesis, red blood cell production, and maintenance of neurological integrity.
Pharmacological Properties
Cyanocobalamin exerts its therapeutic effects by participating in one-carbon metabolism, ensuring proper cellular function, and supporting hematopoiesis and neurologic processes.
Indications for Use
B12 ampoules are indicated for:
- Treating vitamin B12 deficiency
- Managing pernicious anemia
- Alleviating neuropathies associated with vitamin B12 deficiency
Contraindications
Avoid using B12 ampoules if:
- You have a known hypersensitivity to cyanocobalamin or any other components of the formulation
Side Effects
Common side effects may include injection site reactions, mild gastrointestinal disturbances, and hypersensitivity reactions. Consult a healthcare professional for a complete list of potential adverse effects.
Usage Instructions
Recommended Dosage: Administer 1 ampoule intramuscularly once daily. Adhere to aseptic techniques during injection to minimize infection risk.
Benefits Compared to Analogues
B12 ampoules offer rapid absorption and enhanced bioavailability compared to oral B12 supplements, ensuring efficient correction of deficiency states and improved patient outcomes.
Suitable Patient Groups
B12 ampoules are suitable for individuals of all age groups, including pediatric and geriatric populations, who require parenteral vitamin B12 supplementation for various clinical indications.
Storage and Shelf Life
Store B12 ampoules in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use the product beyond the stated shelf life.
Packaging Description
B12 ampoules are typically packaged in boxes containing 10 individual glass ampoules, each labeled with the product name, concentration, and volume for accurate identification and dosing.
Clinical Evidence and Proven Effectiveness
Scientific studies have shown: Cyanocobalamin supplementation effectively treats vitamin B12 deficiency and associated conditions. Notably, research published in the Journal of the American Medical Association (JAMA) demonstrated the efficacy of cyanocobalamin injections in improving neuropathic symptoms in B12-deficient patients.
Pharmacological Effects: Cyanocobalamin’s role in metabolic pathways supports optimal health by aiding in DNA synthesis, red blood cell formation, and neurological function, highlighting its significance in maintaining overall well-being.
Clinical Trials: Comparative trials have indicated that B12 ampoules are equivalent in efficacy to oral B12 supplements for correcting deficiency states, offering the advantage of faster absorption and increased bioavailability, leading to enhanced patient compliance and clinical outcomes.
