Description

Caffeine-Sodium Benzoate Ampoules 20% 1ml. №10

Ingredients

Active ingredient: Caffeine-sodium benzoate 20% in 1ml solution.

Dosage

Dosage: The usual adult dosage is 1 ampoule (1ml) injected intramuscularly or intravenously as directed by a healthcare professional.

Indications

Indications: Caffeine-sodium benzoate is indicated for the treatment of respiratory depression associated with overdose of central nervous system depressants.

Contraindications

Contraindications: Do not use in patients with known hypersensitivity to caffeine or benzoate compounds.

Directions

Directions: Administer the ampoule via intramuscular or intravenous injection. Do not exceed the recommended dosage.

Pharmacological Properties

Caffeine acts as a central nervous system stimulant, counteracting the sedative effects of other drugs. Sodium benzoate enhances the solubility of caffeine, aiding in its rapid absorption and distribution in the body.

Side Effects

Common side effects may include palpitations, tremors, and restlessness. Severe allergic reactions are rare but seek immediate medical attention if they occur.

Benefits Compared to Analogues

Caffeine-sodium benzoate offers a rapid and potent reversal of respiratory depression compared to traditional treatments. Its synergistic action provides a more effective response in emergency situations.

Suitable Patient Groups

This product is suitable for adult patients requiring emergency treatment for respiratory depression due to central nervous system depressant overdose. Use in pediatric or elderly patients should be based on healthcare provider discretion.

Storage and Shelf Life

Store in a cool, dry place away from direct sunlight. Do not freeze. Check the expiration date on the packaging and do not use after the stated shelf life.

Packaging Description

The product is supplied in ampoules containing 1ml of 20% caffeine-sodium benzoate solution. Each package contains 10 ampoules for medical use.

Scientific Evidence

Pharmacological Effects: Caffeine acts as a central nervous system stimulant, counteracting the sedative effects of other drugs. Sodium benzoate enhances the solubility of caffeine, aiding in its rapid absorption and distribution in the body.

Clinical Trials: Studies have shown that the combination of caffeine and sodium benzoate can effectively reverse respiratory depression caused by overdose, making it a valuable emergency treatment option.

Additional Information

Caffeine-sodium benzoate ampoules are a crucial intervention in cases of central nervous system depressant overdose, providing rapid and reliable reversal of respiratory depression. The synergistic action of caffeine and sodium benzoate makes this formulation a potent antidote in emergency settings.

Research has demonstrated the efficacy and safety of caffeine-sodium benzoate in treating respiratory depression, highlighting its importance in critical care and overdose management protocols.