Description
Calimin-60 H (Pyridostigmine Bromide) Tablets
Composition
Each tablet contains pyridostigmine bromide as the active ingredient.
Mechanism of Action
Pyridostigmine bromide inhibits the breakdown of acetylcholine, leading to improved neuromuscular transmission. This mechanism enhances muscle strength and endurance in individuals with myasthenia gravis.
Pharmacological Properties
Pyridostigmine bromide, the active ingredient in Calimin-60 H tablets, acts as a reversible cholinesterase inhibitor, increasing acetylcholine levels at the neuromuscular junction.
Indications for Use
Calimin-60 H tablets are indicated for the treatment of myasthenia gravis, a chronic autoimmune neuromuscular disorder characterized by muscle weakness and fatigue.
Contraindications
Avoid using Calimin-60 H tablets if you are allergic to pyridostigmine bromide or if you have a mechanical intestinal or urinary obstruction. Consult a healthcare provider for alternative treatment options.
Side Effects
Common side effects of Calimin-60 H tablets may include gastrointestinal disturbances, bradycardia, and cholinergic crisis symptoms such as muscle weakness and increased respiratory secretions.
Usage Instructions
The usual adult dose of Calimin-60 H is 60mg to 120mg taken 2 to 4 times daily. Follow the dosage regimen prescribed by your healthcare provider and do not exceed the recommended dose to prevent adverse effects.
Benefits Compared to Analogues
Calimin-60 H offers a reliable and effective treatment option for myasthenia gravis by specifically targeting acetylcholine breakdown, resulting in improved muscle function and quality of life compared to other cholinesterase inhibitors.
Suitable Patient Groups
Calimin-60 H tablets are suitable for adult patients diagnosed with myasthenia gravis. Dosage adjustments may be necessary for elderly individuals or those with renal impairment. Consult a healthcare provider for personalized dosing recommendations.
Storage and Shelf Life
Store Calimin-60 H tablets in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use the product after the specified shelf life has passed.
Packaging Description
Calimin-60 H tablets are available in a vial containing 100 tablets. The packaging is designed to maintain product integrity and protect the tablets from environmental factors that may compromise their quality.
Clinical Evidence and Proven Effectiveness
Studies have demonstrated the efficacy of pyridostigmine bromide in improving muscle strength and function in patients with myasthenia gravis. Research published in reputable journals supports the use of pyridostigmine as a key component in managing this autoimmune neuromuscular disorder.
