Description

Candesar (candesartan cilexetil) tablets 16 mg. №10

Ingredients

Active ingredient: Candesartan cilexetil 16 mg.

Dosage

Dosage: The usual recommended dose is one 16 mg tablet taken once daily.

Indications

Indications: Candesar tablets are indicated for the treatment of hypertension to lower blood pressure.

Contraindications

Contraindications: Do not use Candesar if you are pregnant, have severe liver disease, or have a history of angioedema with previous use of ACE inhibitors.

Directions

Directions: Take Candesar tablets exactly as prescribed by your healthcare provider. Swallow the tablet whole with a glass of water.

Scientific Evidence

Candesartan cilexetil, the active ingredient in Candesar tablets, is a selective angiotensin II receptor blocker that effectively lowers blood pressure by blocking the vasoconstrictor and aldosterone-secreting effects of angiotensin II. Studies have shown that candesartan cilexetil is well-tolerated and effective in reducing blood pressure in patients with hypertension.

Additional Information

It is important to regularly monitor blood pressure levels while taking Candesar tablets to ensure optimal control. Inform your healthcare provider about any other medications you are taking to avoid potential drug interactions.

Pharmacological Effects: Candesartan cilexetil works by blocking the binding of angiotensin II to its receptors, leading to vasodilation and reduced secretion of aldosterone. This mechanism results in decreased peripheral resistance and blood pressure.

Clinical Trials: Clinical trials have demonstrated the efficacy of candesartan cilexetil in reducing cardiovascular events and mortality in patients with hypertension. A study published in the Journal of the American Medical Association (JAMA) showed that candesartan significantly reduced the risk of stroke compared to placebo.