Description

Captopril (captopril) tablets 25 mg. №20

Ingredients

Active ingredient: Captopril 25 mg per tablet.

Dosage

Dosage: The usual starting dose is 25 mg two or three times a day. Your doctor may adjust the dose based on your condition.

Indications

Indications: Captopril is indicated for the treatment of hypertension, heart failure, and to improve survival after a heart attack.

Contraindications

Contraindications: Do not take Captopril if you are pregnant, have a history of angioedema, or are allergic to ACE inhibitors.

Directions

Directions: Take Captopril exactly as prescribed by your doctor. Swallow the tablet whole with a glass of water.

Scientific Evidence

Captopril, an ACE inhibitor, has been extensively studied for its efficacy in treating hypertension and heart failure. Research published in the Journal of the American Medical Association (JAMA) demonstrated that Captopril significantly reduces blood pressure and improves cardiac function in patients with heart failure.

Additional Information

It is important to monitor your blood pressure regularly while taking Captopril. Inform your doctor of any side effects such as dizziness, cough, or swelling. Avoid potassium supplements or salt substitutes containing potassium unless directed by your doctor.

Pharmacological Effects: Captopril works by inhibiting the angiotensin-converting enzyme (ACE), leading to vasodilation and reduced aldosterone secretion. This mechanism helps lower blood pressure and improve cardiac function.

Clinical Trials: Clinical trials have shown that Captopril is effective in reducing mortality and morbidity in patients with heart failure. A study published in the New England Journal of Medicine reported a significant decrease in hospitalizations and symptoms in patients treated with Captopril compared to a placebo group.