Description
Carbamazepin (Carbamazepine) Tablets 0.2 g. №50
Composition
The active ingredient in these tablets is carbamazepine, with each tablet containing 0.2 grams of carbamazepine.
Mechanism of Action
Carbamazepine exerts its therapeutic effects by blocking voltage-gated sodium channels, thereby stabilizing neural membranes and reducing excessive neuronal firing. This mechanism helps in controlling seizures, alleviating nerve pain, and managing bipolar disorder.
Pharmacological Properties
Carbamazepine is an anticonvulsant and mood-stabilizing drug classified as a dibenzazepine derivative. It is absorbed well after oral administration and undergoes hepatic metabolism to active metabolites. The drug has a half-life of approximately 12-17 hours and is primarily excreted in urine.
Indications for Use
Carbamazepin tablets are indicated for the treatment of various conditions, including certain types of seizures, neuropathic pain, and bipolar disorder. It is commonly prescribed to manage trigeminal neuralgia, partial seizures, and as an adjunctive therapy for bipolar disorder.
Contraindications
Carbamazepin tablets are contraindicated in individuals with a known hypersensitivity to carbamazepine or tricyclic compounds. Additionally, patients with a history of bone marrow depression, hepatic porphyria, or atrioventricular block should avoid the use of this medication.
Side Effects
Common side effects associated with carbamazepine therapy include dizziness, drowsiness, nausea, vomiting, and skin rashes. Serious adverse reactions may include agranulocytosis, aplastic anemia, and Stevens-Johnson syndrome. Patients should be monitored for signs of blood dyscrasias and skin reactions.
Usage Instructions
Carbamazepin tablets should be taken orally as directed by the healthcare provider. The dosage regimen varies based on the patient’s condition and response to treatment. It is important not to crush or chew the tablets. If a dose is missed, it should be taken as soon as remembered, unless it is almost time for the next scheduled dose.
Benefits Compared to Analogues
Carbamazepin offers several advantages over other anticonvulsant and mood-stabilizing agents. Its broad spectrum of activity makes it a versatile option for the management of seizures, neuropathic pain, and bipolar disorder. Additionally, the well-established efficacy and safety profile of carbamazepine contribute to its widespread use in clinical practice.
Suitable Patient Groups
Carbamazepin can be used in various patient populations, including adults, adolescents, and elderly individuals. Dosing adjustments may be necessary in elderly patients or those with hepatic impairment. The drug is generally considered safe for use in children above a certain age, under close medical supervision.
Storage and Shelf Life
Carbamazepin tablets should be stored at room temperature, away from moisture and light. The shelf life of the product is typically indicated on the packaging and should be adhered to strictly. Unused or expired tablets should be properly disposed of according to local regulations.
Packaging Description
The carbamazepin tablets are typically packaged in blister packs or amber-colored bottles to protect them from light exposure. Each package contains a specific number of tablets as indicated by the product code. Detailed labeling with instructions for use and safety information is provided on the packaging.
