Description

Carbamazepin forte (carbamazepine) tablets 400 mg. №50

Ingredients

Active ingredient: Carbamazepine 400 mg.

Dosage

Recommended dosage: The usual starting dose is 200 mg twice daily. Dosage may be increased by 200-400 mg per day at weekly intervals based on response. Maximum dose is 1200 mg per day.

Indications

Indicated for: Epilepsy, trigeminal neuralgia, and bipolar disorder.

Contraindications

Do not use if: Hypersensitive to carbamazepine or tricyclic antidepressants.

Directions

– Take with food to minimize gastrointestinal irritation.
– Swallow the tablets whole with a full glass of water.
– Do not crush or chew the tablets.

Scientific Evidence

Carbamazepine has been extensively studied for its efficacy in the treatment of epilepsy and trigeminal neuralgia. Research published in the Journal of Neurology, Neurosurgery & Psychiatry has shown that carbamazepine is effective in controlling seizures and reducing the frequency of episodes in patients with epilepsy. Additionally, a study in the Journal of Pain Research demonstrated the effectiveness of carbamazepine in managing trigeminal neuralgia, a condition characterized by severe facial pain.

Additional Information

– **Warnings:** Carbamazepine may cause dizziness or drowsiness. Avoid driving or operating machinery until you know how this medication affects you.
– **Storage:** Store at room temperature away from moisture and heat.
– **Pregnancy:** Consult your doctor before using carbamazepine during pregnancy as it may harm the unborn baby.

Pharmacological Effects: Carbamazepine works by reducing the excessive electrical activity in the brain that leads to seizures. It does this by blocking sodium channels, stabilizing the overexcited nerve cells.

Clinical Trials: Clinical trials have shown that carbamazepine is effective in the management of bipolar disorder, reducing the frequency and severity of manic and depressive episodes. A study published in the Journal of Clinical Psychopharmacology demonstrated the efficacy of carbamazepine in stabilizing mood and preventing relapses in patients with bipolar disorder.