Description
Cardiodaron (Amiodarone) Tablets 0.2 g. №10
Composition
The main active ingredient in Cardiodaron tablets is amiodarone. Each tablet contains 0.2 grams of amiodarone.
Mechanism of Action
Amiodarone works by blocking potassium channels, sodium channels, and calcium channels in cardiac tissues, thereby prolonging the action potential duration and refractory period. This helps in regulating abnormal heart rhythms.
Pharmacological Properties
Amiodarone exhibits antiarrhythmic properties by affecting cardiac ion channels and adrenergic receptors. It also possesses mild negative inotropic effects and vasodilatory properties.
Indications for Use
Cardiodaron tablets are indicated for the treatment of various types of cardiac arrhythmias, including ventricular and supraventricular tachycardias in patients with structurally normal hearts or underlying heart disease.
Contraindications
- Hypersensitivity to amiodarone or any other ingredients in the tablets.
- Cardiogenic shock or severe sinus node dysfunction.
- Pregnancy and breastfeeding, as amiodarone may harm the fetus or nursing infant.
Side Effects
Common side effects of Cardiodaron tablets may include photosensitivity, thyroid dysfunction, pulmonary toxicity, gastrointestinal disturbances, and neurological effects. Regular monitoring is essential to detect and manage potential adverse effects.
Usage Instructions
Cardiodaron tablets are to be taken orally with a full glass of water. The usual starting dose is one tablet (0.2 g) once or twice a day, as directed by the healthcare provider. The tablets should be swallowed whole and not crushed or chewed.
Benefits Compared to Analogues
Cardiodaron, with its unique pharmacological profile, offers a broad spectrum of antiarrhythmic effects compared to traditional antiarrhythmic agents. It is particularly effective in managing refractory ventricular arrhythmias and atrial fibrillation with rapid ventricular response.
Suitable Patient Groups
Cardiodaron can be used in adult patients with cardiac arrhythmias, including those with structural heart disease. However, caution is advised in pediatric populations and elderly patients due to the potential for increased sensitivity and age-related organ dysfunction.
Storage and Shelf Life
Store Cardiodaron tablets in a cool, dry place away from direct sunlight. Ensure proper sealing of the packaging to prevent moisture exposure. Check the expiration date on the packaging and do not use the tablets beyond the specified shelf life.
Packaging Description
Cardiodaron tablets are typically packaged in blister packs of 10 tablets each. The packaging should include essential information such as the drug name, strength, dosage instructions, batch number, and expiry date for patient safety and regulatory compliance.