Description
Carvidex (Carvedilol) Coated Tablets 25 mg. №20
Composition
The active ingredient in Carvidex is carvedilol. Each coated tablet contains 25 mg of carvedilol.
Mechanism of Action
Carvedilol is a non-selective beta-blocker and alpha-1 blocker. It works by blocking the action of certain natural substances in the body, such as epinephrine, on the heart and blood vessels. This leads to a decrease in heart rate, blood pressure, and strain on the heart.
Pharmacological Properties
Carvedilol’s dual action as a beta-blocker and alpha-1 blocker results in vasodilation, reduced cardiac workload, and improved cardiac function. It also exhibits antioxidant properties and may have anti-inflammatory effects.
Indications for Use
Carvidex is indicated for the treatment of:
- High blood pressure (hypertension)
- Heart failure
- Left ventricular dysfunction following a heart attack
Contraindications
Carvidex is contraindicated in patients with:
- Asthma or related breathing conditions
- Severe liver disease
- Heart block or sick sinus syndrome (unless equipped with a pacemaker)
- Certain types of circulation problems
Side Effects
Common side effects of Carvidex may include dizziness, fatigue, low blood pressure, and slow heart rate. Serious side effects such as worsening heart failure or difficulty breathing should be promptly reported to a healthcare provider.
Usage Instructions
Carvidex should be taken with food to improve absorption and reduce the risk of stomach upset. The usual starting dose is 6.25 mg twice daily. The dosage may be adjusted based on the individual’s response to treatment. It is important to swallow the tablet whole, without crushing or chewing it. If a dose is missed, it should be taken as soon as remembered, unless it is close to the next scheduled dose.
Benefits Compared to Analogues
Carvidex offers the advantage of dual beta-blocking and alpha-1 blocking properties, providing comprehensive cardiovascular benefits in conditions such as hypertension and heart failure. Its antioxidant and potential anti-inflammatory effects further contribute to its therapeutic profile compared to some single-action beta-blockers.
Suitable Patient Groups
Carvidex is suitable for adult patients with hypertension, heart failure, or left ventricular dysfunction post-heart attack. It may be used in elderly patients under appropriate medical supervision. However, caution is advised in patients with certain respiratory conditions or severe liver impairment.
Storage Conditions and Shelf Life
Carvidex should be stored at room temperature away from light and moisture. The tablets have a shelf life of [insert shelf life here] and should not be used beyond the expiration date printed on the packaging.
Packaging Description
Carvidex is available in blister packs containing 20 coated tablets of 25 mg strength each. The packaging is designed to protect the tablets from environmental factors and maintain their stability until use.
