Description
Carvidex (Carvedilol) Coated Tablets 6.25 mg. №20
Composition
The active ingredient in Carvidex tablets is carvedilol 6.25 mg. Each tablet also contains several inactive ingredients to maintain its form and effectiveness.
Mechanism of Action
Carvedilol, the active ingredient in Carvidex, is a non-selective beta-blocker with alpha-blocking activity. It works by blocking beta receptors in the heart and blood vessels, leading to a decrease in heart rate, blood pressure, and workload on the heart.
Pharmacological Properties
Carvedilol exhibits antihypertensive, antiarrhythmic, and neuroprotective properties. It also has antioxidant effects and can improve cardiac function in heart failure patients.
Indications for Use
Carvidex is indicated for the treatment of high blood pressure (hypertension), heart failure, and post-myocardial infarction to improve survival and reduce the risk of cardiovascular events.
Contraindications
Carvidex is contraindicated in patients with severe liver disease, second- or third-degree atrioventricular block, sick sinus syndrome, severe heart failure, and those who are hypersensitive to carvedilol or any component of the formulation.
Side Effects
Common side effects of Carvidex may include dizziness, fatigue, bradycardia, hypotension, and fluid retention. Rare but serious side effects may include worsening heart failure, bronchospasm, and hepatotoxicity.
Usage Instructions
Carvidex should be taken orally with food to enhance absorption and minimize gastrointestinal side effects. The typical starting dose is one tablet (6.25 mg) twice daily, which may be adjusted by a healthcare provider based on individual response.
Benefits Compared to Analogues
Carvidex offers the advantage of combined beta and alpha-blocking properties, which can provide better control of blood pressure and heart function compared to beta-blockers without alpha-blocking activity. Its neuroprotective and antioxidant effects further contribute to its unique benefits.
Suitable Patient Groups
Carvidex can be used in adult patients with hypertension, heart failure, or post-myocardial infarction. It may also be suitable for elderly patients; however, dosing adjustments may be necessary based on individual health status and renal function.
Storage and Shelf Life
Carvidex tablets should be stored at room temperature away from moisture and heat. The shelf life of the product is typically mentioned on the packaging and should be checked before use to ensure efficacy.
Packaging Description
Carvidex is available in blister packs containing 20 coated tablets of 6.25 mg strength. The packaging should be intact and sealed before use to maintain the quality of the tablets.
