Description
Carvium (Carvedilol) Tablets 12.5 mg. №30
Composition
The active ingredient in Carvium tablets is carvedilol. Each tablet contains 12.5 mg of carvedilol.
Mechanism of Action
Carvedilol is a non-selective beta-blocker and alpha-1 blocker. It works by blocking beta receptors in the heart and blood vessels, leading to decreased heart rate and blood pressure. Additionally, it blocks alpha-1 receptors, causing vasodilation.
Pharmacological Properties
Carvedilol has both alpha and beta-adrenergic blocking effects. It also exhibits antioxidant properties and vasodilatory actions, contributing to its anti-hypertensive and anti-arrhythmic effects.
Indications for Use
- Treatment of high blood pressure (hypertension)
- Management of heart failure
- Prevention of heart attack (myocardial infarction)
Contraindications
Carvium is contraindicated in patients with:
- Known hypersensitivity to carvedilol or any of the tablet ingredients
- Severe liver disease
- Certain types of heart rhythm problems
Side Effects
Common side effects of Carvium may include dizziness, fatigue, low blood pressure, and bradycardia. Patients should consult their healthcare provider if these side effects persist or worsen.
Usage Instructions
The usual starting dose of Carvium is 12.5 mg once daily. The dosage may be adjusted based on the patient’s response and tolerance. It is recommended to take Carvium with food to enhance absorption and reduce the risk of gastrointestinal side effects. The tablets should be swallowed whole and not crushed or chewed.
Benefits Compared to Analogues
Carvium offers the advantage of dual alpha and beta-adrenergic blocking properties, making it effective in managing both hypertension and heart failure. Its antioxidant effects further contribute to its cardiovascular benefits compared to other beta-blockers.
Suitable Patient Groups
Carvium is suitable for adult patients with hypertension, heart failure, or at risk of myocardial infarction. It may also be prescribed for elderly patients under careful monitoring due to potential age-related changes in drug metabolism and response.
Storage and Shelf Life
Carvium should be stored at room temperature away from moisture and heat. The shelf life of the tablets is typically indicated on the packaging and should be checked before use.
Packaging Description
Carvium tablets are typically packaged in blister packs or bottles containing 30 tablets. The packaging should be kept intact until the tablets are ready for consumption to maintain their quality and integrity.
