Description
Cefma (Cefpodoxime) Coated Tablets 200 mg. №10
Composition
The active ingredient in Cefma is Cefpodoxime, a third-generation cephalosporin antibiotic. Each tablet contains 200 mg of Cefpodoxime.
Mechanism of Action
Cefpodoxime inhibits bacterial cell wall synthesis by binding to specific penicillin-binding proteins, resulting in bacterial cell lysis and death.
Pharmacological Properties
Cefpodoxime exhibits broad-spectrum antibacterial activity against a variety of Gram-positive and Gram-negative bacteria. It is well-absorbed orally and reaches therapeutic concentrations in various tissues and body fluids.
Indications for Use
Cefma is indicated for the treatment of bacterial infections, including but not limited to:
- Respiratory tract infections
- Skin and soft tissue infections
- Urinary tract infections
Contraindications
Cefma is contraindicated in patients with a history of hypersensitivity to cefpodoxime or other cephalosporin antibiotics. It should be used with caution in patients with renal impairment and appropriate dose adjustments should be made.
Side Effects
Common side effects of Cefma may include gastrointestinal disturbances, allergic reactions, and skin rashes. Serious adverse effects are rare but may include Clostridium difficile-associated diarrhea and anaphylaxis.
Usage Instructions
Cefma tablets should be taken orally with food to improve absorption. The typical adult dosage is one 200 mg tablet every 12 hours. Dosage adjustments may be necessary based on the severity of the infection and the patient’s renal function.
Benefits Compared to Analogues
Cefma offers the advantage of a convenient dosing regimen with twice-daily administration, making it a suitable option for patients requiring outpatient antibiotic therapy. Its broad spectrum of activity covers a wide range of common bacterial pathogens.
Suitable Patient Groups
Cefma is generally well-tolerated across different age groups, including children and the elderly. However, dosage adjustments may be needed in patients with renal impairment to prevent potential adverse effects.
Storage and Shelf Life
Cefma tablets should be stored at room temperature away from moisture and heat. The shelf life of the product is typically indicated on the packaging and should be checked before use.
Packaging Description
Cefma tablets are typically packaged in blister packs to ensure individual tablet integrity and protection from external factors. Each package contains a specified number of tablets as indicated by the product number.
