Description
Cefotaxim (Cefotaxime) Powder 1g. N5 Vial
Ingredients
The main active ingredient in this product is Cefotaxime, a third-generation cephalosporin antibiotic.
Mechanism of Action
Cefotaxime exerts its bactericidal effect by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins, leading to cell lysis and death.
Pharmacological Properties
Cefotaxime has a broad spectrum of activity against Gram-positive and Gram-negative bacteria. It is stable in the presence of beta-lactamases, enhancing its effectiveness against resistant strains.
Indications for Use
Cefotaxime is indicated for the treatment of various bacterial infections, including but not limited to:
- Respiratory tract infections
- Skin and soft tissue infections
- Urinary tract infections
- Gonorrhea
- Meningitis
Contraindications
Cefotaxime is contraindicated in patients with a known hypersensitivity to cephalosporin antibiotics. Caution is advised in individuals with renal impairment to prevent potential adverse reactions.
Side Effects
Common side effects of Cefotaxime may include gastrointestinal disturbances, hypersensitivity reactions, and superinfection. Monitoring for adverse effects is essential during treatment.
Usage Instructions
Cefotaxime should be administered under the supervision of a healthcare professional. The typical adult dosage is 1g via intravenous or intramuscular route every 12 hours. Dosage adjustments may be necessary based on the infection type and severity.
Benefits Compared to Analogues
Cefotaxime offers advantages over some analogues due to its extended spectrum of activity and stability against beta-lactamases, making it effective against a wider range of bacterial strains, including those resistant to other antibiotics.
Suitable Patient Groups
Cefotaxime can be used in various patient populations, including pediatric and elderly individuals, with appropriate dosage adjustments based on age, weight, and renal function. Close monitoring is crucial for optimal therapeutic outcomes.
Storage and Shelf Life
The product should be stored in a cool, dry place away from direct sunlight. The shelf life of Cefotaxime powder is typically indicated on the packaging and should be strictly adhered to for potency and efficacy.
Packaging Description
Cefotaxime powder is commonly available in vials containing 1g of the active ingredient. The packaging should include clear labeling with dosage instructions, expiration date, and necessary cautionary information.
