Description
Ceftriaxon (Ceftriaxone) Powder for Solution for Injections 0.5 g. №1 Vial
Composition
The active ingredient in this product is Ceftriaxone, with each vial containing 0.5 g of Ceftriaxone.
Mechanism of Action
Ceftriaxone, a cephalosporin antibiotic, exerts its bactericidal effect by inhibiting bacterial cell wall synthesis, leading to bacterial cell death.
Pharmacological Properties
Ceftriaxone demonstrates broad-spectrum activity against various Gram-positive and Gram-negative bacteria. It exhibits high stability against beta-lactamases, enhancing its efficacy.
Indications for Use
Ceftriaxone is indicated for the treatment of infections caused by susceptible bacteria, including respiratory, urinary tract, skin, and soft tissue infections, as well as septicemia and meningitis.
Contraindications
- Patients with a history of hypersensitivity to cephalosporins should avoid using Ceftriaxone.
- Neonates requiring calcium-containing IV solutions should not receive Ceftriaxone due to the risk of precipitation.
- Pregnant and breastfeeding women should seek medical advice before initiating Ceftriaxone therapy.
Side Effects
Common side effects of Ceftriaxone may include diarrhea, nausea, vomiting, rash, and allergic reactions. Serious adverse effects such as pseudomembranous colitis and anaphylaxis are rare but possible.
Usage Instructions
Ceftriaxone is administered via intramuscular or intravenous injection. The dosage and duration of treatment should be determined by the prescribing healthcare provider based on the specific infection and patient factors.
Advantages Over Analogues
Ceftriaxone offers the advantage of once-daily dosing due to its long half-life, simplifying treatment regimens and improving patient compliance compared to some other antibiotics in the same class.
Suitable Patient Groups
Ceftriaxone is suitable for use in various patient populations, including pediatric and elderly patients, with appropriate dosage adjustments based on age, weight, and renal function.
Storage and Shelf Life
Ceftriaxone should be stored at controlled room temperature away from light and moisture. The product has a shelf life of X years when stored as directed.
Packaging Description
The product is supplied in single-dose vials containing 0.5 g of Ceftriaxone powder for reconstitution. Each vial is for one-time use only.
