Description
Cefuroxim SAN (Cefuroxime) Coated Tablets 500 mg. №14
Composition
The active ingredient in Cefuroxim SAN is Cefuroxime, a second-generation cephalosporin antibiotic. Each coated tablet contains 500 mg of Cefuroxime.
Mechanism of Action
Cefuroxime, the active ingredient in Cefuroxim SAN, exerts its bactericidal effect by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins.
Pharmacological Properties
Cefuroxim SAN exhibits broad-spectrum antibacterial activity against various Gram-positive and Gram-negative bacteria. It is stable in the presence of beta-lactamases and is well-absorbed after oral administration.
Indications for Use
Cefuroxim SAN is indicated for the treatment of various bacterial infections, including:
- Respiratory tract infections
- Skin and soft tissue infections
- Urinary tract infections
- Gonorrhea
- Lyme disease
Contraindications
Cefuroxim SAN is contraindicated in patients with a history of hypersensitivity to cefuroxime or other cephalosporin antibiotics. Caution is advised in patients with severe renal impairment due to the potential for accumulation of the drug.
Side Effects
Common side effects of Cefuroxim SAN may include gastrointestinal disturbances, allergic reactions, and superinfection. Severe adverse reactions such as anaphylaxis and pseudomembranous colitis have been reported rarely.
Usage Instructions
Cefuroxim SAN should be taken orally with food to optimize absorption. The recommended adult dosage is 1-2 tablets twice a day. Swallow the tablets whole with a full glass of water. If a dose is missed, it should be taken as soon as remembered, unless it is almost time for the next dose.
Benefits Compared to Analogues
Cefuroxim SAN offers the advantage of a broad antibacterial spectrum, stability against beta-lactamases, and convenient twice-daily dosing compared to some other cephalosporin antibiotics.
Suitable Patient Groups
Cefuroxim SAN is suitable for use in both adult and pediatric populations. Dosing adjustments may be necessary in elderly patients and those with renal impairment based on individual considerations.
Storage and Shelf Life
Cefuroxim SAN should be stored at controlled room temperature away from moisture and light. The shelf life of the product is as indicated on the packaging.
Packaging Description
Cefuroxim SAN is available in blister packs containing 14 coated tablets of 500 mg strength each. The packaging is designed to ensure product integrity and protection from external factors.