Description

Ciclosporin Alcaloidsoft (ciclosporin) capsules 50 mg. №50

Ingredients

Active ingredient: Ciclosporin 50 mg.

Dosage

Dosage: The usual starting dose is 2.5 mg/kg/day divided into two doses. Dosage may vary based on individual patient factors.

Indications

Indications: Ciclosporin Alcaloidsoft is indicated for the prophylaxis of organ rejection in kidney, liver, and heart allogeneic transplants.

Contraindications

Contraindications: Do not use in patients with a hypersensitivity to ciclosporin or any component of the formulation.

Directions

Directions: Take Ciclosporin Alcaloidsoft capsules orally, usually twice daily, at the same times each day. Do not crush or chew the capsules.

Scientific Evidence

Ciclosporin, the active ingredient in Ciclosporin Alcaloidsoft, is a potent immunosuppressive agent that acts by inhibiting the production and release of interleukin-2 and other cytokines essential for T-cell activation. This mechanism helps prevent organ rejection in transplant patients.

Several studies have demonstrated the efficacy of ciclosporin in improving graft survival rates and reducing the incidence of acute rejection episodes in transplant recipients. For example, a study published in the American Journal of Transplantation showed that ciclosporin-based immunosuppression significantly improved long-term outcomes in kidney transplant patients.

Additional Information

• Storage: Store at room temperature away from light and moisture.
• Pregnancy: Use during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Overall, Ciclosporin Alcaloidsoft (ciclosporin) capsules 50 mg. №50 offer a reliable option for transplant patients requiring immunosuppressive therapy. The medication’s well-established pharmacological effects and proven efficacy make it a valuable choice in preventing organ rejection and improving patient outcomes post-transplant.

Clinical trials have consistently shown the effectiveness of ciclosporin in enhancing graft survival and minimizing rejection episodes, highlighting its importance in modern transplant medicine. Patients can trust Ciclosporin Alcaloidsoft to provide the necessary immunosuppression while under medical supervision.