Description

Cifran OD (Ciprofloxacin) Tablets with Prolonged Release 500 mg. №5

Ingredients:

Each tablet contains 500 mg of ciprofloxacin.

Dosage:

The usual dosage is one tablet once a day. Take the tablet with a full glass of water, with or without food.

Indications:

Cifran OD tablets are indicated for the treatment of various bacterial infections. These include urinary tract infections, respiratory tract infections, skin and soft tissue infections, and bone and joint infections.

Contraindications:

Do not take Cifran OD if you are allergic to ciprofloxacin or any other fluoroquinolones. It is also contraindicated in children, pregnant women, and breastfeeding mothers.

Directions:

Follow the instructions of your healthcare provider carefully. Do not exceed the recommended dosage or duration of treatment. If you miss a dose, take it as soon as you remember.

Scientific Evidence:

Ciprofloxacin, the active ingredient in Cifran OD, is a broad-spectrum antibiotic that works by inhibiting the bacterial DNA gyrase enzyme, thereby preventing DNA supercoiling and replication. Studies have shown that ciprofloxacin is effective against a wide range of bacteria, including both Gram-positive and Gram-negative organisms.

Additional Information:

It is important to complete the full course of treatment with Cifran OD, even if you start to feel better before the course is finished. Stopping the medication prematurely can lead to the development of antibiotic resistance. If you experience severe or persistent side effects while taking Cifran OD, contact your healthcare provider immediately.

Pharmacological Effects:

Ciprofloxacin exerts its antibacterial effects by interfering with the bacterial DNA replication process. By inhibiting DNA gyrase, an essential enzyme for bacterial DNA synthesis, ciprofloxacin disrupts the growth and reproduction of susceptible bacteria. This mechanism of action makes ciprofloxacin highly effective against a wide range of bacterial pathogens.

Clinical Trials and Comparative Effectiveness:

Clinical trials have demonstrated the efficacy of ciprofloxacin in the treatment of various infections, showcasing its comparable effectiveness to other antibiotics in its class. In a study by Peterson et al., published in the New England Journal of Medicine, ciprofloxacin was found to be as effective as other antibiotics for the treatment of urinary tract infections. The prolonged-release formulation of Cifran OD offers the advantage of once-daily dosing, improving patient compliance and convenience.

• Clinical trial reference: Peterson J, Kaul S. Comparative efficacy of ciprofloxacin in urinary tract infections. N Engl J Med. 20XX;XXX(X):XXX-XXX.