Description
Ciprofarm Dex (Ciprofloxacin, Dexamethasone) Ear Drops 7.5 ml Vial
Ingredients
Active Ingredients: Ciprofloxacin and Dexamethasone.
Mechanism of Action
Ciprofarm Dex combines the antimicrobial action of ciprofloxacin with the anti-inflammatory properties of dexamethasone. Ciprofloxacin inhibits bacterial DNA gyrase, thereby disrupting DNA replication and transcription. Dexamethasone, a corticosteroid, suppresses inflammation by inhibiting the release of inflammatory mediators.
Pharmacological Properties
The combination of ciprofloxacin and dexamethasone in Ciprofarm Dex provides a synergistic effect in treating bacterial ear infections with inflammation. Ciprofloxacin exhibits broad-spectrum antibacterial activity, while dexamethasone reduces inflammation and swelling in the ear canal.
Indications for Use
Indicated for: Treatment of bacterial ear infections with inflammation caused by susceptible organisms.
Contraindications
Do not use Ciprofarm Dex if: allergic to ciprofloxacin, dexamethasone, or any components of the product. Avoid use in patients with viral or fungal ear infections.
Side Effects
Common side effects of Ciprofarm Dex may include temporary stinging or burning sensation in the ear, altered taste sensation, or mild irritation. Rarely, allergic reactions such as itching, rash, or swelling may occur. Contact a healthcare provider if any adverse reactions persist or worsen.
Usage Instructions
Dosage: Instill 4 drops into the affected ear twice daily or as directed by a healthcare professional. Ensure the vial is at room temperature before use. Shake the vial gently before instilling the drops.
Administration: Tilt the head sideways, instill the prescribed number of drops into the ear canal, and keep the head tilted for a few minutes to allow proper distribution of the medication.
Benefits Compared to Analogues
Ciprofarm Dex offers a dual-action approach by combining the antibacterial and anti-inflammatory effects in a single formulation, providing a more comprehensive treatment for bacterial ear infections compared to individual agents. The synergistic effect of ciprofloxacin and dexamethasone enhances efficacy and reduces the need for multiple medications.
Suitable Patient Groups
Ciprofarm Dex is suitable for use in adults, adolescents, and children above a certain age as determined by a healthcare professional. Special caution should be exercised in pediatric and elderly patients to ensure appropriate dosing and monitoring.
Storage and Shelf Life
Store Ciprofarm Dex ear drops at controlled room temperature between 15°C to 30°C (59°F to 86°F). Avoid exposure to excessive heat or direct sunlight. Keep the vial tightly closed and out of reach of children. Check the expiration date on the packaging and do not use the product if expired.
Packaging Description
Ciprofarm Dex is supplied in a 7.5 ml vial for easy dispensing and administration. The vial is made of a sterile material to maintain the integrity of the product. Each vial is sealed for protection and should be discarded after completing the prescribed course of treatment.
Clinical Evidence and Proven Effectiveness
Clinical studies have shown the efficacy of ciprofloxacin and dexamethasone in treating acute otitis media, emphasizing the importance of combination therapy in managing ear infections. The antimicrobial and anti-inflammatory properties of Ciprofarm Dex have been demonstrated to reduce bacterial growth and inflammation in the ear canal, leading to improved clinical outcomes.
