Description

Citomoxan (moxifloxacin, hydrochloride) eye drops 0,5% 5 mg. №1

Ingredients

Active ingredient: Moxifloxacin hydrochloride 5 mg per 1 ml.

Dosage

Dosage: Instill 1 drop in the affected eye(s) every 4-6 hours for the first 2 days, then reduce to 1 drop 2-3 times daily.

Indications

Indications: Citomoxan eye drops are indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of microorganisms.

Contraindications

Contraindications: Do not use in patients with a history of hypersensitivity to moxifloxacin or any other components of the formulation.

Directions

Directions: Wash hands before use. Tilt the head back, pull the lower eyelid down, and instill the prescribed number of drops. Close the eye for a few minutes without blinking.

Scientific Evidence

Citomoxan eye drops containing moxifloxacin have shown significant efficacy in the treatment of bacterial conjunctivitis. Studies have demonstrated the bactericidal activity of moxifloxacin against a wide range of pathogens commonly implicated in eye infections, including Staphylococcus aureus and Streptococcus pneumoniae.

Additional Information

It is important to complete the full course of treatment as prescribed by the healthcare provider to ensure the complete eradication of the infection. If symptoms persist or worsen, discontinue use and consult a healthcare professional for further evaluation.

Pharmacological Effects: Moxifloxacin, a fluoroquinolone antibiotic, exerts its action by inhibiting bacterial DNA gyrase and topoisomerase IV enzymes, leading to the disruption of DNA replication and transcription, ultimately causing bacterial cell death.

Clinical Trials: Clinical trials have shown that Citomoxan eye drops provide rapid relief of symptoms associated with bacterial conjunctivitis and have a favorable safety profile. Patients treated with moxifloxacin eye drops experienced a significant improvement in signs and symptoms compared to placebo.