Description

Citramon-M (acetylsalicylic acid, paracetamol, caffeine) tablets №6

Ingredients

Active ingredients: Acetylsalicylic acid, Paracetamol, Caffeine.

Dosage

Adults: Take 1-2 tablets every 4-6 hours as needed. Do not exceed 6 tablets in 24 hours.

Indications

Citramon-M tablets are indicated for the relief of mild to moderate pain such as headache, toothache, menstrual cramps, and muscle aches.

Contraindications

Do not use Citramon-M tablets if you:

• Are allergic to any of the ingredients
• Have a history of stomach ulcers
• Have severe liver or kidney disease

Directions

Take the tablets orally with a full glass of water. Do not crush or chew the tablets. Consult a doctor for use in children under 12 years of age.

Scientific Evidence

Citramon-M combines the analgesic properties of acetylsalicylic acid and paracetamol with the stimulant effects of caffeine. Studies have shown that this combination provides effective pain relief with a faster onset of action compared to individual components alone.

Additional Information

It is important to follow the recommended dosage and not exceed the maximum daily limit to avoid potential side effects. If symptoms persist, consult a healthcare professional for further evaluation.

Pharmacological Effects: Acetylsalicylic acid and paracetamol work by inhibiting the production of prostaglandins, which are chemicals in the body that cause pain and inflammation. Caffeine acts as a central nervous system stimulant, enhancing the pain-relieving effects of the other ingredients.

Clinical Trials: A randomized controlled trial published in the Journal of Pain Research demonstrated the superior efficacy of a combination of acetylsalicylic acid, paracetamol, and caffeine in managing acute pain compared to individual components. The study highlighted the synergistic effects of the three ingredients in providing rapid and effective pain relief.