Description
Clabel (Clarithromycin) Coated Tablets 500 mg. №14
Composition
Active ingredient: Clarithromycin 500 mg.
Inactive ingredients: microcrystalline cellulose, croscarmellose sodium, povidone, magnesium stearate, hypromellose, talc, titanium dioxide, polyethylene glycol.
Mechanism of Action
Clarithromycin, a macrolide antibiotic, inhibits bacterial protein synthesis, thereby exerting its bacteriostatic effect against susceptible microorganisms.
Pharmacological Properties
Clarithromycin demonstrates broad-spectrum activity against various bacteria, making it effective in treating respiratory tract infections, skin and soft tissue infections, and Helicobacter pylori infections.
Indications for Use
Clabel (Clarithromycin) coated tablets are indicated for bacterial infections caused by susceptible microorganisms, including respiratory tract infections, skin and soft tissue infections, and Helicobacter pylori eradication to reduce the risk of duodenal ulcer recurrence.
Contraindications
Do not use Clabel (Clarithromycin) if:
- You are allergic to clarithromycin or any other macrolide antibiotics.
- You are taking colchicine in patients with renal or hepatic impairment.
- You are taking medications such as ergotamine or dihydroergotamine.
Side Effects
Common side effects of Clabel tablets may include nausea, diarrhea, and abdominal pain. Contact your healthcare provider if you experience severe or persistent adverse reactions.
Usage Instructions
Recommended Dosage: The usual dose is 500 mg twice daily, taken with food. Follow the specific dosing instructions provided by your healthcare provider.
Swallow the tablet whole with a full glass of water. Do not crush or chew the tablet. Complete the full course of treatment even if symptoms improve.
Benefits Compared to Analogues
Clabel (Clarithromycin) offers a broad spectrum of activity against various bacterial infections, providing effective treatment options for patients with respiratory, skin, and Helicobacter pylori-related conditions.
Suitable Patient Groups
Clabel tablets can be used in various patient groups, including adults, children (under healthcare provider guidance), and the elderly, with appropriate dosage adjustments as needed.
Storage and Shelf Life
Store Clabel tablets at room temperature, away from moisture and heat. Keep out of reach of children. Do not use the medication after the expiration date indicated on the packaging.
Packaging Description
Clabel tablets are available in blister packs containing 14 coated tablets, each with a clarithromycin strength of 500 mg.
Clinical Evidence and Proven Effectiveness
Clarithromycin has demonstrated efficacy in treating a wide range of bacterial infections, including respiratory tract and skin infections. A study in the Journal of Antimicrobial Chemotherapy confirmed the effectiveness of clarithromycin-based therapy in eradicating Helicobacter pylori, reducing the risk of duodenal ulcer recurrence.