Description

Closart (losartan) Coated Tablets 25 mg. №28

Ingredients

Active ingredient: Losartan potassium 25 mg.
Other ingredients: Lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide, macrogol, talc.

Dosage

Recommended dosage: The usual starting dose is 25 mg once daily. Dosage may be adjusted according to the patient’s response.

Indications

Closart (losartan) Coated Tablets are indicated for the treatment of hypertension and to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy.

Contraindications

Do not use Closart (losartan) Coated Tablets if:

• You are allergic to losartan or any other ingredients in the product.
• You are pregnant as it can cause injury and even death to the unborn baby.
• You have severe liver disease.

Directions

How to take: Swallow the tablet whole with a glass of water. It can be taken with or without food. Follow the instructions of your healthcare provider.

Scientific Evidence

Losartan, the active ingredient in Closart tablets, is an angiotensin II receptor antagonist that blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II. Clinical studies have shown that losartan is effective in reducing blood pressure and has a good safety profile. Research published in the Journal of Hypertension demonstrated the efficacy of losartan in reducing cardiovascular events in hypertensive patients.

Additional Information

Closart (losartan) Coated Tablets are well-tolerated by most patients. However, it is essential to monitor blood pressure regularly while taking this medication. Inform your doctor about any side effects or concerns. Avoid potassium supplements or salt substitutes containing potassium unless advised by your healthcare provider.

Pharmacological effects of losartan include vasodilation, decreased vascular resistance, and reduced aldosterone secretion. By blocking angiotensin II receptors, losartan helps in lowering blood pressure and improving overall cardiovascular health.

Closart (losartan) has been compared to other antihypertensive medications like ACE inhibitors and has shown similar efficacy in blood pressure control with potentially fewer side effects. Consult your doctor to determine the most suitable treatment option for your condition.