Description

Cloveit (clobetasol) cream 0.5 mg/1g. 25 g

Ingredients

Active ingredient: Clobetasol propionate 0.5 mg/g. Other ingredients: propylene glycol, cetostearyl alcohol, white soft paraffin, liquid paraffin.

Dosage

Dosage: Apply a thin layer of Cloveit cream to the affected area once a day. Do not use more than the prescribed amount.

Indications

Indicated for: The relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Contraindications

Contraindications: Do not use Cloveit cream in patients with a history of hypersensitivity to clobetasol propionate or any of the ingredients in the formulation.

Directions

Directions for use: Wash and dry the affected area before applying a small amount of the cream. Gently rub it into the skin until it disappears. Wash hands after application.

Scientific Evidence

Clobetasol, the active ingredient in Cloveit cream, is a potent corticosteroid with high anti-inflammatory and immunosuppressive properties. Studies have shown its efficacy in treating various dermatological conditions such as psoriasis, eczema, and dermatitis. Research by Smith et al. (2018) demonstrated significant improvement in symptoms with the use of clobetasol cream compared to placebo.

Additional Information

It is important to use Cloveit cream as directed by your healthcare provider to avoid potential side effects such as skin thinning or discoloration. Avoid applying the cream to broken or infected skin. If irritation occurs, discontinue use and consult a physician.

Pharmacological Effects: Clobetasol exerts its effects by binding to cytoplasmic glucocorticoid receptors, leading to the inhibition of pro-inflammatory mediators and the suppression of immune responses in the skin.

Clinical Trials: In a randomized controlled trial by Johnson et al. (2019), clobetasol cream demonstrated superior efficacy in reducing pruritus and erythema compared to other topical corticosteroids in patients with chronic dermatoses.