Description

Co-Diroton tablets 20 mg/12.5 mg. №30

Ingredients

Co-Diroton tablets contain 20 mg of enalapril maleate and 12.5 mg of hydrochlorothiazide as active ingredients.

Dosage

The recommended dosage of Co-Diroton is one tablet once daily. It is important to follow the instructions provided by your healthcare provider.

Indications

Co-Diroton tablets are indicated for the treatment of hypertension in patients who require dual therapy.

Contraindications

Do not use Co-Diroton tablets if you are allergic to any of the ingredients, have a history of angioedema related to previous treatment with ACE inhibitors, or if you are pregnant.

Directions

Take Co-Diroton tablets exactly as prescribed by your doctor. Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.

Scientific Evidence

Studies have shown that the combination of enalapril and hydrochlorothiazide in Co-Diroton tablets is effective in lowering blood pressure in patients with hypertension. Research published in the Journal of Clinical Hypertension demonstrated the superior efficacy of the combination therapy compared to monotherapy.

Additional Information

It is important to monitor your blood pressure regularly while taking Co-Diroton tablets. Inform your doctor of any side effects or concerns. Avoid consuming alcohol while on this medication.

Pharmacological Effects: Enalapril works by inhibiting the angiotensin-converting enzyme, leading to vasodilation and reduced blood pressure. Hydrochlorothiazide acts as a diuretic, promoting the excretion of sodium and water, further lowering blood pressure.

Clinical Trials: Clinical trials have demonstrated the efficacy and safety of Co-Diroton tablets in managing hypertension. A randomized controlled trial published in the American Journal of Medicine showed a significant reduction in blood pressure levels with the use of Co-Diroton compared to placebo.