Description
Co-Irbesan (Irbesartan, Hydrochlorothiazide) Coated Tablets 300 mg/12.5 mg. №28
Ingredients
Each coated tablet contains 300 mg of irbesartan and 12.5 mg of hydrochlorothiazide.
Mechanism of Action
Irbesartan, an angiotensin II receptor blocker, and hydrochlorothiazide, a thiazide diuretic, work synergistically to lower blood pressure. Irbesartan blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II, while hydrochlorothiazide reduces plasma volume.
Pharmacological Properties
The combination of irbesartan and hydrochlorothiazide acts on different pathways to effectively reduce blood pressure in hypertensive patients.
Indications for Use
Co-Irbesan tablets are indicated for the treatment of hypertension in patients not adequately controlled with monotherapy.
Contraindications
Do not use Co-Irbesan if you are pregnant, have severe renal impairment, or are allergic to any of the components in the formulation.
Side Effects
Possible side effects of Co-Irbesan may include electrolyte imbalances, dizziness, and allergic reactions. Consult a healthcare professional if any adverse reactions occur.
Usage Instructions
The recommended dosage is one tablet daily, to be taken orally with a glass of water. It can be taken with or without food, as directed by a healthcare provider.
Benefits Compared to Analogues
The combination of irbesartan and hydrochlorothiazide has been shown to be more effective in reducing blood pressure compared to using either component alone. This dual therapy provides better control and management of hypertension.
Suitable Patient Groups
Co-Irbesan can be used in adult patients with hypertension. Dosage adjustments may be necessary for specific populations such as the elderly or those with certain medical conditions. Consult a healthcare provider for personalized recommendations.
Storage and Shelf Life
Store Co-Irbesan in a cool, dry place away from direct sunlight. Keep the tablets in the original packaging to protect them from moisture. Check the expiration date on the packaging and do not use the product beyond that date.
Packaging Description
Co-Irbesan tablets are supplied in a package containing 28 coated tablets. The packaging is designed to maintain the stability and integrity of the tablets until use.
Clinical Evidence and Proven Effectiveness
Studies have demonstrated the efficacy of Co-Irbesan in reducing cardiovascular events in patients with hypertension. The combination of irbesartan and hydrochlorothiazide has shown to provide better blood pressure control and cardiovascular protection compared to individual components alone.
