Description

Co-Prenesa Tablets 8 mg/2.5 mg

Composition

Active ingredients: Perindopril tert-butylamine, Indapamide

Mechanism of Action

Perindopril, an ACE inhibitor, inhibits the angiotensin-converting enzyme, resulting in vasodilation and reduced aldosterone secretion. Indapamide, a thiazide-like diuretic, promotes diuresis and vasodilation by inhibiting sodium reabsorption in the distal convoluted tubule. The combined action of these components effectively controls blood pressure and provides cardiovascular protection.

Pharmacological Properties

Co-Prenesa tablets combine the actions of perindopril and Indapamide to achieve comprehensive cardiovascular protection and blood pressure management.

Indications for Use

Indicated for: Hypertension and heart failure.

Contraindications

Do not use if: Allergic to any component, history of angioedema related to previous ACE inhibitor therapy.

Side Effects

Common side effects may include dizziness, headache, and dry cough. Consult a healthcare professional for a full list of possible side effects.

Usage Instructions

Dosage: One tablet daily, or as directed by a healthcare professional.

Directions for use: Swallow the tablet whole with water, preferably in the morning.

Benefits Compared to Analogues

Co-Prenesa tablets have been shown to provide superior cardiovascular protection and blood pressure control compared to other antihypertensive agents.

Suitable Patient Groups

Co-Prenesa tablets are suitable for adult patients with hypertension and heart failure. Consult a healthcare professional for use in specific patient populations such as children or the elderly.

Storage and Shelf Life

Storage: Store in a cool, dry place away from direct sunlight.

Packaging Description

Each pack contains 90 tablets of Co-Prenesa 8 mg/2.5 mg.

Clinical Evidence and Proven Effectiveness

Clinical trials have shown that the combination of perindopril and Indapamide in Co-Prenesa tablets effectively lowers blood pressure and reduces the risk of cardiovascular events in patients with hypertension. The synergistic effect of these two components provides comprehensive cardiovascular protection.

Additional Information

Precautions: Regular monitoring of blood pressure and renal function is recommended during treatment with Co-Prenesa tablets. Avoid use in pregnancy and breastfeeding.