Description

Concor (Bisoprolol Fumarate) Coated Tablets 5 mg. №30

Composition:

Each tablet contains 5 mg of bisoprolol fumarate as the active ingredient.

Mechanism of Action:

Bisoprolol, a selective beta-blocker, blocks the action of adrenaline on the heart, resulting in a slower heart rate and reduced strain on the heart muscle. This mechanism is beneficial in managing hypertension, angina pectoris, and heart failure.

Pharmacological Properties:

Bisoprolol fumarate exerts its pharmacological effects by selectively blocking beta-1 adrenergic receptors in the heart, leading to decreased heart rate and contractility. It also helps in reducing peripheral vascular resistance, thereby lowering blood pressure.

Indications for Use:

Concor tablets are indicated for the treatment of hypertension, angina pectoris, and heart failure in patients requiring beta-blocker therapy.

Contraindications:

Concor tablets should not be used in individuals with a history of bronchospasm, severe bradycardia, or cardiogenic shock. Patients with these conditions may be at increased risk of adverse effects.

Side Effects:

Common side effects of Concor tablets may include dizziness, fatigue, and cold extremities. If any severe or persistent side effects occur, consult a healthcare professional for further evaluation.

Usage Instructions:

The typical dosage regimen involves taking one tablet of Concor (5 mg) per day, as prescribed by a healthcare provider. The tablet should be swallowed whole with a glass of water, with or without food.

Benefits Compared to Analogues:

Concor tablets offer advantages over other beta-blockers due to their selective beta-1 blocking properties, which result in a reduced risk of bronchoconstriction and peripheral vasoconstriction. This selectivity makes Concor a preferred choice in patients with concurrent respiratory conditions or peripheral vascular disease.

Suitable Patient Groups:

Concor tablets are suitable for adult patients, including the elderly population, who require beta-blocker therapy for the management of cardiovascular conditions. However, individual dosing adjustments may be necessary based on age, renal function, and comorbidities.

Storage and Shelf Life:

• Storage: Keep Concor tablets at room temperature, protected from moisture and heat to maintain their stability and efficacy.
• Shelf Life: Check the packaging for the expiration date and do not use the tablets beyond this date to ensure safety and effectiveness.

Packaging Description:

Concor tablets are packaged in blister packs containing 30 coated tablets. Each tablet is individually sealed to maintain product integrity and protect against environmental factors.

Clinical Evidence and Proven Effectiveness:

Bisoprolol, the active ingredient in Concor tablets, has been extensively studied in clinical trials. Evidence supports its efficacy in reducing blood pressure, improving exercise tolerance in angina patients, and decreasing hospitalizations in heart failure patients. Clinical studies have demonstrated the overall cardiovascular benefits of bisoprolol therapy, making it a valuable treatment option in cardiovascular medicine.