Description

Cordaron (amiodaronum) solution for injections 50 mg/ml. 3 ml. ampoules №6

Ingredients

Each 3 ml ampoule contains 150 mg of amiodarone hydrochloride as the active ingredient.

Dosage

The usual dose is 5 mg/kg infused over 20 to 120 minutes. Dosage may vary based on the patient’s condition and response to treatment.

Indications

Cordaron injections are indicated for the treatment of life-threatening recurrent ventricular arrhythmias. It is used when other antiarrhythmic agents have failed.

Contraindications

Do not use Cordaron injections in patients with cardiogenic shock, severe sinus-node dysfunction, or second- or third-degree atrioventricular block. It is contraindicated in patients with a known hypersensitivity to amiodarone.

Directions

Administer Cordaron injections intravenously only by healthcare professionals experienced in the treatment of life-threatening arrhythmias. Monitor the patient’s ECG and blood pressure during administration.

Scientific Evidence

Amiodarone is a Class III antiarrhythmic agent with a complex pharmacological profile. It prolongs the action potential duration and refractory period in myocardial tissues, leading to its antiarrhythmic effects. Studies have shown that amiodarone is effective in treating various ventricular arrhythmias, including ventricular tachycardia and ventricular fibrillation.

Additional Information

Amiodarone has been extensively studied in clinical trials for its efficacy and safety profile. Research has demonstrated its superiority over other antiarrhythmic agents in certain patient populations. However, due to its potential for serious side effects, including pulmonary toxicity and thyroid dysfunction, careful monitoring is essential during treatment with Cordaron injections.

Overall, Cordaron (amiodaronum) solution for injections is a valuable option in the management of life-threatening ventricular arrhythmias. Its proven efficacy and unique pharmacological actions make it a crucial component in the treatment armamentarium for such conditions.