Description
Corinfar (Nifedipine) Retard Tablets with Prolonged Release 20 mg. №30 Blister
Composition
Active ingredient: Nifedipine 20 mg.
Other ingredients: lactose monohydrate, cellulose microcrystalline, colloidal anhydrous silica, magnesium stearate.
Mechanism of Action
Nifedipine, the active ingredient in Corinfar retard tablets, is a calcium channel blocker that works by relaxing and widening blood vessels. This action helps to lower blood pressure and improve blood flow to the heart, reducing the workload on the heart muscle.
Pharmacological Properties
The pharmacological properties of nifedipine include its ability to selectively inhibit calcium ion influx across cell membranes in cardiac and smooth muscle. This leads to vasodilation and decreased peripheral vascular resistance, resulting in reduced blood pressure and increased oxygen delivery to the heart.
Indications for Use
Corinfar (Nifedipine) Retard Tablets are indicated for the treatment of hypertension (high blood pressure) and angina pectoris (chest pain).
Contraindications
Do not use Corinfar (Nifedipine) Retard Tablets if:
- You are allergic to nifedipine or any other ingredients in the product.
- You have severe hypotension (low blood pressure).
- You are pregnant or breastfeeding without medical advice.
Side Effects
Common side effects of Corinfar (Nifedipine) Retard Tablets may include headache, dizziness, flushing, edema, and palpitations. Contact your healthcare provider if you experience any persistent or severe side effects.
Usage Instructions
Adults: The usual dose is one tablet every 12 hours. Dosage may vary depending on individual response to treatment. Swallow the tablets whole with a glass of water. Do not crush or chew the tablets. Follow the prescribed dosage and instructions provided by your healthcare provider.
Benefits Compared to Analogues
Corinfar (Nifedipine) Retard Tablets offer the benefit of a prolonged-release formulation, providing consistent blood levels and prolonged therapeutic effects. Clinical trials have shown comparable efficacy and safety profiles with other antihypertensive agents, along with the convenience of once-daily dosing for improved compliance.
Suitable Patient Groups
Corinfar (Nifedipine) Retard Tablets are suitable for adult patients with hypertension or angina pectoris. Special caution should be exercised when prescribing to pregnant or breastfeeding individuals, and dosage adjustments may be necessary for elderly patients or those with hepatic impairment.
Storage and Shelf Life
Store Corinfar (Nifedipine) Retard Tablets in a cool, dry place away from direct sunlight. Keep the blister pack tightly closed when not in use. Check the expiration date on the packaging and do not use the product after the specified shelf life.
Packaging Description
Corinfar (Nifedipine) Retard Tablets are available in blister packs containing 30 tablets of 20 mg strength each. The packaging is designed to protect the tablets from moisture and maintain their stability until use.
