Description

Corinfar UNO (nifedipine) tablets with prolonged release 40 mg. №50

Ingredients

Active ingredient: Nifedipine 40 mg.
Other ingredients: lactose monohydrate, cellulose microcrystalline, colloidal anhydrous silica, magnesium stearate.

Dosage

Recommended dosage: 1 tablet daily, swallowed whole with a glass of water. Do not crush or chew the tablet.

Indications

Corinfar UNO tablets are indicated for the treatment of hypertension (high blood pressure) and angina (chest pain).

Contraindications

Do not use Corinfar UNO tablets if you have a known allergy to nifedipine or any of the other ingredients in the tablet. Consult your doctor before use if you have low blood pressure or liver problems.

Directions

Take Corinfar UNO tablets exactly as prescribed by your healthcare provider. Do not exceed the recommended dosage.

Scientific Evidence

Nifedipine, the active ingredient in Corinfar UNO tablets, is a calcium channel blocker that works by relaxing the blood vessels, making it easier for the heart to pump blood. Studies have shown that nifedipine is effective in lowering blood pressure and reducing the frequency of angina attacks.

Additional Information

It is important to monitor your blood pressure regularly while taking Corinfar UNO tablets. Inform your doctor of any side effects or concerns. Avoid grapefruit or grapefruit juice while using this medication as it may interact and lead to unwanted side effects.

Pharmacological Effects: Nifedipine blocks calcium from entering the muscle cells of the heart and blood vessels. This action results in the relaxation of blood vessels, lowering blood pressure and improving blood flow to the heart muscle.

Clinical Trials: Clinical trials have demonstrated the efficacy of nifedipine in the management of hypertension and angina. A study published in the Journal of Clinical Pharmacology showed that nifedipine effectively reduced blood pressure in patients with hypertension.