Description

Coriol (carvedilol) tablets 12.5 mg. №28

Ingredients

Active ingredient: Carvedilol 12.5 mg.
Other ingredients: lactose monohydrate, maize starch, povidone K30, crospovidone, magnesium stearate.

Dosage

Recommended dosage: The usual dose is 12.5 mg twice daily. Dosage may be increased gradually to 25 mg twice daily.

Indications

Coriol tablets are indicated for the treatment of hypertension, heart failure, and left ventricular dysfunction following myocardial infarction.

Contraindications

Do not use Coriol tablets if:

• You are allergic to carvedilol or any other ingredients in the product.
• You have severe liver disease.
• You have asthma or other breathing problems.

Directions

How to take: Swallow the tablets whole with a glass of water, with or without food. Do not crush or chew the tablets.

Scientific Evidence

Carvedilol is a non-selective beta-blocker with additional alpha-blocking properties. It has been extensively studied in various clinical trials for its efficacy in treating hypertension, heart failure, and post-myocardial infarction patients. Research has shown that carvedilol reduces mortality and hospitalizations in heart failure patients and improves left ventricular function.

Clinical trials have demonstrated the benefits of carvedilol in reducing cardiovascular events and improving outcomes in patients with heart failure. The COMET trial compared carvedilol with another beta-blocker and showed a significant reduction in mortality with carvedilol.

Additional Information

Precautions: It is important to monitor blood pressure and heart rate regularly while taking Coriol tablets. Avoid sudden withdrawal of the medication as it may worsen your condition.

Storage: Store at room temperature away from moisture and heat. Keep out of reach of children.