Description
Coriol (Carvedilol) Tablets 25 mg. №28
Composition
Active ingredient: Carvedilol 25 mg
Mechanism of Action
Carvedilol, the active ingredient in Coriol tablets, is a non-selective beta-blocker with alpha-blocking properties. It works by decreasing the heart rate and dilating blood vessels, which helps to lower blood pressure and improve heart function.
Pharmacological Properties
Carvedilol exerts its effects through its action on beta-adrenergic receptors and alpha1-adrenergic receptors. By blocking these receptors, it reduces sympathetic activity, leading to decreased heart rate and vasodilation.
Indications for Use
Coriol tablets are indicated for the treatment of hypertension, heart failure, and left ventricular dysfunction following a heart attack.
Contraindications
Do not use Coriol tablets if you have severe liver impairment, asthma, or certain heart conditions that may be exacerbated by beta-blockade.
Side Effects
Common side effects of Carvedilol may include dizziness, fatigue, low blood pressure, and bradycardia. It is important to report any unusual symptoms to your healthcare provider.
Usage Instructions
Take Coriol tablets exactly as prescribed by your doctor. The usual dose is 25 mg twice daily with food. Do not stop taking the medication suddenly without consulting your healthcare provider.
Benefits Compared to Analogues
Carvedilol has been shown to offer benefits in heart failure beyond those of traditional beta-blockers. Its alpha-blocking properties may provide additional advantages in certain patient populations.
Suitable Patient Groups
Coriol tablets are suitable for adults of all ages, including the elderly. Dosage adjustments may be necessary in patients with renal impairment.
Storage and Shelf Life
Store Coriol tablets in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use the product after it has expired.
Packaging Description
Coriol tablets are packaged in blister packs of 28 tablets each. Each tablet contains 25 mg of Carvedilol and is marked for easy identification.
Scientific Evidence
Several studies have demonstrated the efficacy of Carvedilol in the treatment of heart failure and hypertension. A meta-analysis published in the Journal of the American College of Cardiology found that Carvedilol reduced the risk of hospitalization and death in patients with heart failure compared to placebo.
Additional Information
It is important to monitor your blood pressure and heart rate regularly while taking Coriol tablets. Inform your doctor of any changes in your condition or if you experience any side effects. Discuss with your healthcare provider about any other medications or supplements you are taking before starting Coriol tablets to avoid potential drug interactions.
