Description
Crestor (Rosuvastatin) Coated Tablets 10 mg. №28
Ingredients:
Each tablet contains 10 mg of rosuvastatin as the active ingredient.
Mechanism of Action:
Rosuvastatin works by inhibiting HMG-CoA reductase, the enzyme responsible for cholesterol production in the liver. This inhibition leads to a reduction in cholesterol levels, particularly LDL cholesterol, in the bloodstream.
Pharmacological Properties:
The pharmacological effects of Crestor involve its ability to decrease cholesterol synthesis in the liver, resulting in lowered LDL cholesterol levels. This mechanism aids in preventing the formation of arterial plaque, thereby reducing the risk of cardiovascular diseases like heart attacks and strokes.
Indications for Use:
Crestor tablets are indicated for the treatment of high cholesterol and triglycerides. Additionally, they are prescribed to lower the risk of heart attacks and strokes in individuals with cardiovascular conditions.
Contraindications:
It is contraindicated to take Crestor if pregnant or breastfeeding. Patients with liver disease or unexplained persistently elevated liver enzymes should also avoid using this medication.
Side Effects:
Common side effects of Crestor may include muscle pain, weakness, abdominal pain, and nausea. In rare cases, severe side effects like liver problems or rhabdomyolysis (muscle breakdown) can occur.
Usage Instructions:
The recommended dosage of Crestor is 10 mg once daily. The tablet should be swallowed whole with a glass of water and can be taken with or without food. It is essential to follow the healthcare provider’s instructions for optimal results.
Benefits Compared to Analogues:
Rosuvastatin has been demonstrated to be more potent in reducing LDL cholesterol levels compared to other statins. Its efficacy in lowering the risk of cardiovascular events has been supported by clinical studies, making it a preferred choice in high-risk individuals.
Suitable Patient Groups:
Crestor is suitable for a wide range of patient groups, including adults, the elderly, and individuals with cardiovascular conditions. However, dosages may need adjustment based on individual health status and medical history.
Storage Conditions and Shelf Life:
Crestor should be stored at room temperature away from moisture and heat. The shelf life of the medication is typically indicated on the packaging and should be adhered to for optimal efficacy.
Packaging Description:
Crestor is available in blister packs containing 28 coated tablets, with each tablet clearly labeled with the dosage strength of 10 mg of rosuvastatin.
Clinical Evidence and Proven Effectiveness:
Studies have shown that rosuvastatin effectively lowers LDL cholesterol levels and reduces the incidence of cardiovascular events. Research published in reputable journals like the New England Journal of Medicine and the Journal of the American Medical Association has highlighted the efficacy of rosuvastatin in improving cardiovascular outcomes.
