Description

Dalacin C (Clindamycin) Capsules 300 mg. №16

Composition

Active Ingredient: Clindamycin (as clindamycin hydrochloride).

Mechanism of Action

Clindamycin, a lincosamide antibiotic, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of susceptible bacteria, leading to the suppression of bacterial growth and eventual eradication of the infection.

Pharmacological Properties

Clindamycin demonstrates a broad spectrum of activity against both aerobic and anaerobic bacteria. It is known for its excellent tissue penetration, making it effective in treating deep-seated infections.

Indications for Use

Indicated for: Treatment of serious infections caused by susceptible anaerobic bacteria.

Contraindications

Contraindicated in: Patients with a history of hypersensitivity to clindamycin or lincomycin.

Side Effects

Common side effects may include gastrointestinal disturbances, allergic reactions, and skin rashes. Patients should seek medical attention if they experience severe diarrhea or persistent symptoms.

Usage Instructions

Administration: Swallow the capsule whole with a full glass of water to prevent esophageal irritation.

Dosage: The usual dose ranges from 150-450 mg every 6 hours, depending on the severity of the infection. Dosage adjustments may be necessary based on individual patient factors.

Benefits Compared to Analogues

Dalacin C offers a potent treatment option for various bacterial infections with proven efficacy and a well-established safety profile. Its broad spectrum of activity and tissue penetration make it a preferred choice in clinical practice.

Suitable Patient Groups

This medication is suitable for adults and children over a certain age, as determined by the healthcare provider. Dosage adjustments may be required for elderly patients or those with renal or hepatic impairment.

Storage and Shelf Life

Store in a cool, dry place away from direct sunlight. Keep out of reach of children. Check the expiration date on the packaging and do not use the product beyond that date.

Packaging Description

Dalacin C capsules are available in a package containing 16 capsules of 300 mg strength each. The packaging is designed to ensure the integrity and stability of the product.

Clinical Evidence and Proven Effectiveness

Clindamycin has been extensively studied and proven effective in various infections, including skin and soft tissue infections, respiratory tract infections, and bone and joint infections. Clinical trials have shown comparable or superior outcomes with clindamycin compared to other antibiotics. For instance, a study by Brook, et al., highlighted the high efficacy of clindamycin in skin and soft tissue infections with a favorable safety profile.